GATE Simulation of $^{12}{\rm C}$ Hadrontherapy Treatment Combined With a PET Imaging System for Dose Monitoring: A Feasibility Study

Jan, S.; Frisson, T.; Sarrut, David

doi:10.1109/tns.2012.2233496

Cited by 15 publications

(11 citation statements)

References 34 publications

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“…A comparison between results and data from the literature obtained using different codes (MCNP, EGS, FLUKA, ETRAN, GEPTS, and PENELOPE) showed a general agreement within 6%. An additional DPK dataset was then generated for other radionuclides of interest ( 67 Ga, 68 Ga, 123 I, 124 I, 125 I, 153 Sm, 186 Re, and 188 Re). The conclusion is that current MC codes-including GATE-now provide equivalent results for "standard" situations, involving photon/electron transport for energies of interest in nuclear medicine.…”

Section: A1 Dose Point Kernelmentioning

confidence: 99%

“…In Ref. 123, the authors simulated with GATE a carbon ion beam plan coupled with a complete PET ECAT EXACT HR+ system and demonstrated the need for simulating the full PET system instead of only smoothing the simulated positron emitter maps using a Gaussian function. Differences in the distal position of the signal fall-off of 20% were observed between the full PET system simulation and a simple convolution model.…”

Section: F2 Hadron-pet Studiesmentioning

confidence: 99%

“…The importance of precise modeling of the detailed features of the imaging devices for ensuring accurate predictions from the simulations has been demonstrated in Ref. 123.…”

Section: F3 Prompt-gamma Studiesmentioning

confidence: 99%

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A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

Sarrut¹,

Bardiès²,

Boussion³

et al. 2014

Med. Phys.

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386

263

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In this paper, the authors' review the applicability of the open-source GATE Monte Carlo simulation platform based on the GEANT4 toolkit for radiation therapy and dosimetry applications. The many applications of GATE for state-of-the-art radiotherapy simulations are described including external beam radiotherapy, brachytherapy, intraoperative radiotherapy, hadrontherapy, molecular radiotherapy, and in vivo dose monitoring. Investigations that have been performed using GEANT4 only are also mentioned to illustrate the potential of GATE. The very practical feature of GATE making it easy to model both a treatment and an imaging acquisition within the same framework is emphasized. The computational times associated with several applications are provided to illustrate the practical feasibility of the simulations using current computing facilities.

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Section: A1 Dose Point Kernelmentioning

confidence: 99%

Section: F2 Hadron-pet Studiesmentioning

confidence: 99%

See 1 more Smart Citation

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

Sarrut¹,

Bardiès²,

Boussion³

et al. 2014

Med. Phys.

Self Cite

386

263

View full text Add to dashboard Cite

show abstract

“…It has been developed by the OpenGate collaboration and encapsulates the GEANT4 libraries, providing a toolkit mostly oriented to nuclear medicine by easily including detailed geometry of many imaging devices. It has been tested in the context of particle therapy, especially for range monitoring applications [24][25][26].…”

Section: Geant4mentioning

confidence: 99%

Challenges in Monte Carlo Simulations as Clinical and Research Tool in Particle Therapy: A Review

2020

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The use and interest in Monte Carlo (MC) techniques in the field of medical physics have been rapidly increasing in the past years. This is the case especially in particle therapy, where accurate simulations of different physics processes in complex patient geometries are crucial for a successful patient treatment and for many related research and development activities. Thanks to the detailed implementation of physics processes in any type of material, to the capability of tracking particles in 3D, and to the possibility of including the most important radiobiological effects, MC simulations have become an essential calculation tool not only for dose calculations but also for many other purposes, like the design and commissioning of novel clinical facilities, shielding and radiation protection, the commissioning of treatment planning systems, and prediction and interpretation of data for range monitoring strategies. MC simulations are starting to be more frequently used in clinical practice, especially in the form of specialized codes oriented to dose calculations that can be performed in short time. The use of general purpose MC codes is instead more devoted to research. Despite the increased use of MC simulations for patient treatments, the existing literature suggests that there are still a number of challenges to be faced in order to increase the accuracy of MC calculations for patient treatments. The goal of this review is to discuss some of these remaining challenges. Undoubtedly, it is a work for which a multidisciplinary approach is required. Here, we try to identify some of the aspects where the community involved in applied nuclear physics, radiation biophysics, and computing development can contribute to find solutions. We have selected four specific challenges: i) the development of models in MC to describe nuclear physics interactions, ii) modeling of radiobiological processes in MC simulations, iii) developments of MC-based treatment planning tools, and iv) developments of fast MC codes. For each of them, we describe the underlying problems, present selected examples of proposed solutions, and try to give recommendations for future research.

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“…The developments provided new features, such as the modeling of moving sources and motion, thus allowing for IMRT and arc therapy applications. A carbon ion therapy application combining radiation therapy modeling and emission tomography was presented as a proof of concept of the combined imaging and dosimetric, time-resolved, capabilities of the GATE platform 2,4 . In this paper, the terminology Light Ion Beam Therapy (LIBT) is used 5 .…”

Section: Introductionmentioning

confidence: 99%

Technical Note: GATE‐RTion: a GATE/Geant4 release for clinical applications in scanned ion beam therapy

et al. 2020

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Purpose: GATE-RTion is a validated version of GATE for clinical use in the field of Light Ion Beam Therapy. This paper describes the GATE-RTion project and illustrates its potential through clinical applications developed in three European centers delivering scanned proton and carbon ion treatments. Methods: GATE-RTion is a collaborative framework provided by the OpenGATE collaboration. It contains a validated GATE release based on a specific Geant4 version, a set of tools to integrate GATE into a clinical environment and a network for clinical users. Results: Three applications are presented: Proton radiography applications at the Centre Antoine Lacassagne (Nice, France); Independent dose calculation for proton therapy at the Christie NHS Foundation Trust (Manchester, UK); Independent dose calculation system for protons and carbon ions at the MedAustron Ion Therapy center (Wiener Neustadt, Austria). Conclusions: GATE-RTion builds the bridge between researchers and clinical users from the OpenGATE collaboration in the field of Light Ion Beam Therapy. The applications presented in three European facilities using three completely different machines (three different vendors, cyclotron and synchrotron-based systems, protons and carbon ions) demonstrate the relevance and versatility of this project.

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GATE Simulation of $^{12}{\rm C}$ Hadrontherapy Treatment Combined With a PET Imaging System for Dose Monitoring: A Feasibility Study

Cited by 15 publications

References 34 publications

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

Challenges in Monte Carlo Simulations as Clinical and Research Tool in Particle Therapy: A Review

Technical Note: GATE‐RTion: a GATE/Geant4 release for clinical applications in scanned ion beam therapy

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