GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia (Schumach) and Pterocarpus angolensis (DC)

Abstract

The non-polar components of two leguminoceae species Albizia adianthifolia (Schumach), and Pterocarpus angolensis (DC) were investigated. GC-MS analysis of the crude n-hexane and chloroform extracts together with several chromatographic separation techniques led to the identification and characterization (using NMR) of sixteen known compounds from the heartwood and stem bark of Albizia adianthifolia and Pterocarpus angolensis respectively. These constituents include, n-hexadecanoic acid (palmitic acid) 1, oleic acid 2, chondrillasterol 3, stigmasterol 4, 24S 5α-stigmast-7-en-3β-ol 5, 9,12-octadecadienoic acid (Z,Z)-, methyl ester 6, trans-13-octadecanoic acid, methyl ester 7, tetradecanoic acid 8, hexadecanoic acid, methyl ester 9, octadecanoic acid 10, tetratriacontane 11, 7-dehydrodiosgenin 12, lupeol 13, stigmasta-3,5-diene-7-one 14, friedelan-3-one (friedelin) 15, and 1-octacosanol 16. Using agar over lay method, the preliminary antimicrobial assay for the extracts was carried out against bacterial (E. coli, P. aeruginosa, B. subtilis, S. aueus) and a fungus/yeast (C. albicans) strains. The n-hexane and chloroform extracts of A. adianthifolia showed the best activity against E. coli with minimum inhibition quantity (MIQ) of 1 µg each while the remaining exhibited moderate-to-weak activity against the test microorganisms.

Determination of antioxidant potential ofAcacia niloticaleaf extract in oxidative stress response system ofSaccharomyces cerevisiae

“…The presence of fatty acids and fatty acid esters in ethanolic leaf extract of A. nilotica also suggests their contribution to bioactivities, especially towards ROS scavenging in S. cerevisiae mutants. These results were in accordance with previous reports depicting the antioxidant potential of fatty acids and fatty acid esters …”

Chemical Investigation of Lipoidal Matter of Ficus craterostoma

“…This compound is reported to have antibacterial, antifungal 16 , antioxidant 17 , antiinflammatory, hypocholesterolemic effects 18 . Linolenic acid is an immense bioactive compound having antimicrobial 16 , antimalarial 19 , antidiabetic, anticancer, antiarteriosclerotic effects and used in treatment of obesity 20 .…”

CAROB (Ceratonia siliqua): HEALTH, MEDICINE, CHEMISTRY

“…For example, n-nonadecanol from Schinus lentiscifolius, 185 lupeol from Albizia adianthifolia, 186 genisstein from soybean (Glycine max), 187 geraldone from Flourensia oolepis, 188 and liquiritigenin from Dalbergia odorifera. (Figure 2) from the methnolic extract of Carob leaves.…”