Gebelikte Trombositopeni

Abstract

Thrombocytopenia, which is encountered in 7-10% of pregnancies is characterized with decreased number of thrombocytes. The most frequent cause of thrombocytopenia during pregnancy is gestational thrombocytopenia. These patients usually do not have symptoms due to mild thrombocytopenia. The diagnosis is usually established by excluding connective tissue disorders, drug effects and obstetric causes. The etiology of thrombocytopenia during early pregnancy is most frequently due to autoimmune causes. Thrombocytopenia secondary to obstetric causes like preeclampsia, HELLP syndrome should always be kept in mind. Under these circumstances the thrombocytopenia will not resolve unless pregnancy is terminated. The clinician should be able to distinguish between thrombocytopenia that does not require treatment and the causes that require emergent and serious medical interventions.

Gebelikte Trombositopeni Sebebi ile İstenen Hematoloji Konsültasyonlarına Genel Bakış: Tek Merkez Deneyimi

“…Uluslararası kılavuzlara dayanarak, trombositopeni, trombosit sayısı<150.000 /mikroL olarak tanımlandı (4). Trombositopeni trombosit sayısına göre ciddi (<50.000/mikroL), orta (50.000-100.000/mikroL) ve hafif (>100.000/mikroL) olarak sınıflandırıldı (1)…”

“…Trombosit sayısının 150.000/mikroL'nin altında olması şeklinde tanımlanan trombositopeni (1), gebelikte anemiden sonra karşılaşılan en sık ikinci hematolojik hastalıktır. Gebelerdeki sıklığı %6-10 civarındadır (2) ve preeklamptik gebelerde bu oran %15'lere varabilir (3).…”