Gender-based differences in primary percutaneous coronary intervention in patients with myocardial infarction from a developing country: A retrospective cohort study

Yasmin, Farah; Kumar, Sumeet; Singh, Manjeet; Sagar, Fnu; Kumar, Karan; Asghar, Muhammad Sohaib; Jawed, Fareeha; Kirmani, Tooba Ahmed; Alam, Muhammad Tanveer

doi:10.1016/j.amsu.2022.103532

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…The fundamental mechanisms behind mortality in women patients remain unclear. Earlier published literatures have found the different clinical and outcome characteristics between gender and higher frequency of cardiac risk factors and mortality identified in female population than male [ 5 , 6 ]. Numerous studies have reported that compared to male patients, female patients with STEMI undergoing PAMI had higher mortality, the difference might be attributable to different cardiovascular risk factors.…”

Section: Introductionmentioning

confidence: 99%

The gender spectrum of in-hospital survival post primary percutaneous coronary intervention for ST elevation myocardial infarction: Exploring age-driven trends

Patel,

Vyas,

Natarajan

et al. 2024

Journal of the Saudi Heart Association

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Background The study was aimed to evaluate gender difference and age & gender specific interaction of in-hospital outcomes of patients with ST elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Methods This was a prospective cohort study of 1748 patients with STEMI undergoing primary PCI. The study was dichotomised according to gender to evaluate the difference in the outcome. The study was further stratified based on an age cut-off of 75 years to examine the age-specific gender relationship in survival outcomes. Independent variables for in-hospital mortality were analysed through logistic regression. Results There were 314 (17.96%) females with an average age of 60.80 years and 1434 (82.03%) males with an average age of 54.87 years. The prevalence of diabetes (24.8% vs. 13.2%) and hypertension (33.1% vs. 12.9%) was significantly higher in female patients compared to male patients, whereas the significantly higher number of male patients were smokers. On multivariate analysis, odds of female gender OR = 3.54 (1.37–9.17), killip class >2 OR = 3.05 (1.97–4.71) and baseline creatinine OR = 2.27 (1.22–4.23) were found as significant predictors of in-hospital mortality. The crude odds ratio of 2.35 (1.49–3.72) and adjusted OR of 2.05 (1.27–3.30) for female mortality was significant among patients aged <75-years. While patients with ≥75-years of age, the mortality difference was insignificant. Conclusion Although the incidence of STEMI was higher in male compared to female patients, female patients had two-fold higher in-hospital mortality than male. Female gender was an independent predictor for in-hospital mortality in patients <75-years of age.

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Section: Introductionmentioning

confidence: 99%

The gender spectrum of in-hospital survival post primary percutaneous coronary intervention for ST elevation myocardial infarction: Exploring age-driven trends

Patel,

Vyas,

Natarajan

et al. 2024

Journal of the Saudi Heart Association

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A Cohort Study of the Effects of Integrated Medical and Nursing Rounds Combined with AIDET Communication Mode on Recovery and Quality of Life in Patients Undergoing Percutaneous Coronary Intervention

Yin

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To explore the influence of the communication mode of “Acknowledge, Introduce, Duration, Explanation, and Thanks (AIDET)” on the postoperative recovery and quality of life of patients undergoing percutaneous coronary intervention. Methods. Sixty patients with percutaneous coronary intervention in our hospital from April 2019 to April 2021 were selected. The patients were randomly divided into a control group ( n = 30 ) and research group ( n = 30 ). The control group received integrated medical and nursing rounds, and the research group received integrated medical and nursing rounds combined with AIDET communication mode. The scores of nursing satisfaction, cardiac function, self-nursing ability, short-term prognosis, and quality of life were compared between the two groups. Results. In the comparison of nursing satisfaction between the two groups, the satisfaction of the research group was low in 1 case, moderate in 6 cases, and high in 27 cases, with a satisfaction rate of 96.67%. In the control group, there were 7 cases with low satisfaction, 10 cases with moderate satisfaction, and 13 cases with high satisfaction, with a satisfaction rate of 76.67%. The nursing satisfaction of the research group was higher than that of the control group, and the difference was statistically significant, and the difference was statistically significant ( P < 0.05 ). After intervention, the cardiac function of the two groups was improved. The LVEF and LVESVI of the research group were higher than those of the control group, while the WMSI of the research group was lower than that of the control group ( P < 0.05 ). In the comparison of self-nursing ability, the self-nursing maintenance, self-nursing management, self-nursing confidence, and total score of self-nursing in the research group were significantly higher than those in the control group, and the difference was statistically significant ( P < 0.05 ). The incidence rates of acute myocardial infarction (AMI), revascularization, arrhythmia, heart failure, cardiogenic shock, and cardiac death in the research group were obviously lower than those in the control group, and the difference was statistically significant ( P < 0.05 ). After intervention, the scores of quality of life of the two groups decreased, and the scores of physiological function, psychological function, social function, and health self-cognition in the research group were lower than those in the control group ( P < 0.05 ). Conclusion. Medical and nursing integrated ward rounds combined with AIDET communication mode can effectively improve the prognosis of patients undergoing percutaneous coronary intervention to promote the establishment of a harmonious nurse-patient relationship. The patients’ self-care ability is able to be effectively enhanced.

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Prehospital Factors Contributing to Delays in the Timely Management of ST-Elevation Myocardial Infarction

Gooshvar,

Soleimani,

Nazari

et al. 2024

Jundishapur J Health Sci

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Background: Prehospital factors are critical contributors to delays in managing patients with ST elevation myocardial infarction (STEMI), potentially leading to increased mortality and morbidity. Identifying and addressing these obstacles could significantly reduce the mortality and morbidity of these patients and enhance healthcare performance. Objectives: This study aims to evaluate the prehospital factors associated with delays in primary percutaneous coronary intervention (PPCI) among patients with STEMI. Methods: In this prospective study, 394 STEMI patients treated with PPCI were evaluated, with the interval between symptom onset and the start of the procedure being measured and recorded. Patients were categorized into two groups based on this interval: Appropriate and delayed (< 90 minutes vs. ≥ 90 minutes). The potential predictors of delay were identified and assessed. Results: In this study, 394 STEMI patients were evaluated and categorized into 192 patients with delayed PPCI and 202 patients with on-time PPCI. Multivariate analysis revealed that being female (OR: 1.59, 95% CI: 1.08 - 2.01, P-value: < 0.01), having no past medical history of cardiovascular disease (CVD) (OR: 1.49, 95% CI: 1.09 - 1.90, P-value: < 0.01), no family history of CVD (OR: 1.28, 95% CI: 1.04 - 1.53, P-value: 0.03), a lower education level than academic (OR: 1.44, 95% CI: 1.05 - 1.84, P-value: < 0.01), symptom onset between 18:00 and 06:00 (OR: 1.58, 95% CI: 1.10 - 2.06, P-value: 0.01), and transport by ambulance versus private vehicle (OR: 1.57, 95% CI: 1.07 - 2.08, P-value: < 0.01) were significantly associated with a higher risk of delayed PCI. Conversely, higher socioeconomic status (OR: 0.68, 95% CI: 0.51 - 0.86, P-value: 0.02) and having a caregiver at home (OR: 0.52, 95% CI: 0.32 - 0.72, P-value: < 0.01) were significantly associated with a lower risk of delayed PPCI. Conclusions: Reducing factors that contribute to delays in PPCI can lead to improved public health outcomes and greater health opportunities for the population. Delays in STEMI patients were significantly associated with living in rural areas, lower education levels, and female gender. Conversely, using private vehicles for transport, having a caregiver present, and higher socioeconomic status may reduce the risk of delayed PPCI.

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Gender-based differences in primary percutaneous coronary intervention in patients with myocardial infarction from a developing country: A retrospective cohort study

Cited by 3 publications

References 20 publications

The gender spectrum of in-hospital survival post primary percutaneous coronary intervention for ST elevation myocardial infarction: Exploring age-driven trends

The gender spectrum of in-hospital survival post primary percutaneous coronary intervention for ST elevation myocardial infarction: Exploring age-driven trends

A Cohort Study of the Effects of Integrated Medical and Nursing Rounds Combined with AIDET Communication Mode on Recovery and Quality of Life in Patients Undergoing Percutaneous Coronary Intervention

Prehospital Factors Contributing to Delays in the Timely Management of ST-Elevation Myocardial Infarction

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