Gender Differences in Clinical Characteristics, Treatment and Long-Term Outcome in Patients With Stage C/D Heart Failure in Japan

Sakata, Yasuhiko; Miyata, Satoshi; Nochioka, Kotaro; Miura, Masanobu; Takada, Tsuyoshi; Tadaki, Soichiro; Takahashi, Jun; Shimokawa, Hiroaki

doi:10.1253/circj.cj-13-1009

Cited by 61 publications

(65 citation statements)

References 26 publications

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“…94 Although a number of studies of heart failure patients have indicated that survival rates are better in women than in men, recent research has shown that the long-term prospects for women are not as good as previously thought. 95 Initiatives aimed at improving heart failure prevention should therefore include strategies for reaching out to older people, particularly older women.…”

Section: Infections Chagas Diseasementioning

confidence: 99%

Heart failure: preventing disease and death worldwide

et al. 2014

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Executive Summary Heart failure is a life-threatening disease and addressing it should be considered a global health priority. At present, approximately 26 million people worldwide are living with heart failure. The outlook for such patients is poor, with survival rates worse than those for bowel, breast or prostate cancer. Furthermore, heart failure places great stresses on patients, caregivers and healthcare systems. Demands on healthcare services, in particular, are predicted to increase dramatically over the next decade as patient numbers rise owing to ageing populations, detrimental lifestyle changes and improved survival of those who go on to develop heart failure as the final stage of another disease. It is time to ease the strain on healthcare systems through clear policy initiatives that prioritize heart failure prevention and champion equity of care for all. Despite the burdens that heart failure imposes on society, awareness of the disease is poor. As a result, many premature deaths occur. This is in spite of the fact that most types of heart failure are preventable and that a healthy lifestyle can reduce risk. Even after heart failure has developed, premature deaths could be prevented if people were taught to recognize the symptoms and seek immediate medical attention. Public awareness campaigns focusing on these messages have great potential to improve outcomes for patients with heart failure and ultimately to save lives.

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Section: Infections Chagas Diseasementioning

confidence: 99%

Heart failure: preventing disease and death worldwide

et al. 2014

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“…Therefore, in the present study, we aimed to examine whether statin use is associated with better clinical outcomes in HFpEF patients, using the database of the Chronic Heart Failure Registry and Analysis in the Tohoku district-2 (CHART-2), a multicenter prospective observational study of cardiovascular diseases (CVD) in Japan. [19][20][21][22] …”

Section: Study Outcomes and Definitionsmentioning

confidence: 99%

“…19- 22 Between October 2006 and March 2010, 10,219 consecutive Japanese patients older than 20 years with ACC/ AHA stages B-D of HF 23 or coronary artery disease (CAD) were enrolled in both in-and outpatient settings. 19 The ACC/ AHA stages B-D of HF were defined as follows: Stage B, structural heart disease but without signs or symptoms of HF; Stage C, structural heart disease with prior or current symptoms of HF; Stage D, refractory HF requiring specialized interventions.…”

Section: Data Sourcesmentioning

confidence: 99%

Prognostic Impact of Statin Use in Patients With Heart Failure and Preserved Ejection Fraction

Nochioka

Sakata

Miyata

et al. 2015

Circ J

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“…RDW and RFCA of AF in HF Patients such as β-blockers compared with men with chronic HF. 25 These factors may have contributed to the poor outcomes of female patients with HF who underwent CA of AF in the present study. Surprisingly, the traditional prognostic factors of LAD in both the HF and non-HF groups and plasma BNP level in the HF group were not found to be independent predictors for recurrence of AF after ablation therapy in the present study.…”

Section: Discussionmentioning

confidence: 83%

Elevated Red Blood Cell Distribution Width Predicts Recurrence After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure　– Comparison With Non-Heart Failure Patients –

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Kato

Miyoshi

et al. 2016

Circ J

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Background: Elevated red blood cell distribution width (RDW) predicts poor prognosis in patients with cardiovascular diseases. However, little is known about the association between RDW and outcomes after catheter ablation of atrial fibrillation (AF). Methods and Results:A total of 757 patients who underwent radiofrequency catheter ablation of AF were divided into heart failure (HF, n=79) and non-HF (n=678) groups; RDW was assessed as a predictor after catheter ablation in each. During a 22.3-month follow-up period, the baseline RDW in the HF group was greater in the recurrence group than in the non-recurrence group (14.5±2.0% vs. 13.5±0.9%, P=0.013). In contrast, no significant difference in RDW at baseline was found in the non-HF group between the recurrence and non-recurrence groups (13.3±0.8% vs. 13.2±0.8%, P=0.332, respectively). Multivariate analysis demonstrated that RDW (hazard ratio 1.20, 95% confidence interval 1.01-1.40, P=0.034) was an independent predictor of AF recurrence in the HF group. The cut-off values of RDW for the recurrence of AF and major adverse events in the HF group were 13.9% and 14.8%, respectively. Conclusions:High RDW is an independent predictor for the recurrence of AF and major adverse events in patients with HF after catheter ablation. RDW is a potential noninvasive marker in AF patients complicated with HF. (Circ J 2016; 80: 627 -638)

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Gender Differences in Clinical Characteristics, Treatment and Long-Term Outcome in Patients With Stage C/D Heart Failure in Japan

Cited by 61 publications

References 26 publications

Heart failure: preventing disease and death worldwide

Heart failure: preventing disease and death worldwide

Prognostic Impact of Statin Use in Patients With Heart Failure and Preserved Ejection Fraction

Elevated Red Blood Cell Distribution Width Predicts Recurrence After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure　– Comparison With Non-Heart Failure Patients –

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Gender Differences in Clinical Characteristics, Treatment and Long-Term Outcome in Patients With Stage C/D Heart Failure in Japan

Cited by 61 publications

References 26 publications

Heart failure: preventing disease and death worldwide

Heart failure: preventing disease and death worldwide

Prognostic Impact of Statin Use in Patients With Heart Failure and Preserved Ejection Fraction

Elevated Red Blood Cell Distribution Width Predicts Recurrence After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure – Comparison With Non-Heart Failure Patients –

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Elevated Red Blood Cell Distribution Width Predicts Recurrence After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure　– Comparison With Non-Heart Failure Patients –