Gender differences in the longitudinal associations of depressive symptoms and leisure-time physical activity with cognitive decline in ≥57year-old Taiwanese

Chang, Shujen L.; Tsai, Alan C.

doi:10.1016/j.ypmed.2015.05.001

Cited by 11 publications

(17 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of adjusted analysis indicated that there were no significant patterns in relations between physical activity and cognitive decline in any of the three states. These findings differed from previous research that showed physical activity to be a neuroprotective factor [1][2][3][4][7][8][9].…”

Section: Discussioncontrasting

confidence: 99%

“…Increasing age is known to be associated with cognitive decline through decreased neurotrophic factor expression and neurogenesis in the brain [1]. Substance use and current health status may also affect cognition over time [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

“…For example, tobacco and alcohol use negatively impact many aspects of health, including brain function, which could contribute to cognitive decline and lower levels of cognitive function [3,5]. In addition, stress can counteract neuroprctive influences, leading greater risk for cognitive decline [1,4], and excess sleep could be a symptom of certain disorders, such as depression, that are associated with increased cognitive decline [6].…”

Section: Introductionmentioning

confidence: 99%

“…Exercise also increases VEGF, which is known to be neurogenic and neuroprotective [1]. Both increased leisure-time activity and vigorous physical activity may help reduce the risk of cognitive decline in postmenopausal females [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…There are also inconsistent findings addressing the type and intensity of physical activity that would be most beneficial for cognitive decline [3,4,6,9]. This study aims to assess the relationship between varying levels of physical activity and cognitive decline for females ages 55 to 64.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Current Physical Activity Levels may Not be a Protective Factor for Cognitive Decline in Women Ages 55 to 64

Hussein¹,

Hatfield²,

Valdez³

et al. 2017

J Prev Med

View full text Add to dashboard Cite

Purpose: Physical activity could help prevent or slow deficits in cognition as an individual age; however, little is known about this relationship in females ages 55 to 64. The purpose of this study was to assess the relationship between physical activity levels and cognitive decline in females ages 55 to 64. Methods:This cross sectional analysis used 2015 data from the Behavioral Risk Factor Surveillance System (BRFSS) for females ages 55 to 64 in Connecticut, Montana, and Oregon. Logistic regression was used to assess the relationship between physical activity levels and cognitive decline while controlling for health and demographic factors.Results: Across states, few participants reported cognitive decline (10-14%), and only one-fifth reported being inactive (18-29%), while twice as many reported being highly active (34-48%). Adjusted results indicated that cognitive decline was not found to be significantly related to physical activity levels in any state, but cognitive decline was significantly related to number of health conditions, mental health, and substance use (all with moderate to large effect sizes) in two or three of three states. Conclusion:Across states, cognitive decline was not related to physical activity levels in females ages 55 to 64. The measurement for cognitive decline provided a limited scope of the condition and this study was unable to control for menopause and hormone replacement therapy, which may affect the outcome.Primary providers should not screen for physical activity levels related to cognitive decline in this population, but should screen for cognitive decline, multiple health conditions, current mental health issues, and substance use, if symptoms present for any of these in this target population.Providers should educate patients about the overall benefits of physical activity, but should focus on concurrently managing health conditions and discontinuing tobacco use as related to cognitive decline in females ages 55 to 64.

show abstract