General Anesthesia for Cesarean Delivery in a Patient with Paroxysmal Nocturnal Hemoglobinuria and Thrombocytopenia

Abstract

Pregnancy in patients with paroxysmal nocturnal hemoglobinuria increases the risk of hemolysis, thrombosis, anemia, and thrombocytopenia. We describe the anesthetic management of a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia who underwent general anesthesia for cesarean delivery.

Practice Guidelines for Obstetric Anesthesia

“…Studies with observational findings and case reports suggest that the availability of resources for hemorrhagic emergencies may be associated with reduced maternal complications (Category B3/B4-B evidence). [212][213][214][215][216][217][218][219] Survey Findings: The consultants and ASA members strongly agree that institutions providing obstetric care should have resources available to manage hemorrhagic emergencies.…”