General Method for the Synthesis of Isoxazoline N‐Oxides from Aliphatic Nitro Compounds.

Abstract

Compounds. -Optimal methods are detailed for the synthesis of five-membered cyclic nitronates from aliphatic nitro compounds and olefins. Under certain reaction conditions intermediates of the transformation such as (XII), (XIII) and (XIV) can be isolated. -(KUNETSKY, R. A.; DILMAN*, A. D.; STRUCHKOVA, M. I.; BELYAKOV, P. A.; TARTAKOVSKY, V. A.; IOFFE, S. L.; Synthesis 2006, 13, 2265-2270; Zelinsky Inst. Org. Chem., Russ. Acad. Sci., Moscow 117913, Russia; Eng.) -Mais 45-129

Dearomative pyrrole (3+2) reaction with geminal bromonitroalkane: synthesis of 2,3-dihydropyrroles

“…Sporadically, visible light-catalyzed or Cu(OH) 2 or t -butyldimethylsilyl chloride (TBSCl)-mediated reactions of geminal bromonitroalkanes with terminal alkenes delivering 2-isoxazoline- N -oxides were reported. 11…”