2013
DOI: 10.1134/s1070428013090145
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General procedure for the synthesis of ortho-vinylbenzyl-substituted amines, ethers, and sulfides

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Cited by 4 publications
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“…Several methods have been reported for the synthesis of 2-( N , N -dialkylaminomethyl)styrenes [3946] relying on different approaches: i) from o -vinylbenzyl chloride [43], ii) by the Hofmann cleavage of quaternary tetrahydroisoquinoline salts under the action of silver oxide [39,42] and iii) by a reaction of 2-(2-bromoethyl)benzyl bromide with secondary amines under microwave irradiation followed by the decomposition of the products under the action of potassium tert -butoxide [46]. All of the above routes offer some advantages but they all are rather expensive.…”
Section: Resultsmentioning
confidence: 99%
“…Several methods have been reported for the synthesis of 2-( N , N -dialkylaminomethyl)styrenes [3946] relying on different approaches: i) from o -vinylbenzyl chloride [43], ii) by the Hofmann cleavage of quaternary tetrahydroisoquinoline salts under the action of silver oxide [39,42] and iii) by a reaction of 2-(2-bromoethyl)benzyl bromide with secondary amines under microwave irradiation followed by the decomposition of the products under the action of potassium tert -butoxide [46]. All of the above routes offer some advantages but they all are rather expensive.…”
Section: Resultsmentioning
confidence: 99%