Generalisability in economic evaluation studies in healthcare: a review and case studies

Abstract

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Cost effectiveness of high-risk HPV DNA testing for cervical cancer screening in South Africa

“…As a result we have excluded screening methods such as direct visual inspection and liquid-based cytology, as these approaches have demonstrated sensitivity comparable to conventional cytology [51]. Finally, our results may not be generalizable to countries other than South Africa since our model relied on country-specific data and assumptions regarding epidemiology, infrastructure, and costs [52,53].…”

Cuestiones controvertidas en evaluación económica (I): perspectiva y costes de intervenciones sanitarias

“…La segunda cuestión, métodos y opciones de valoración más adecuados de los recursos sanitarios (costes unitarios) en las evaluaciones económicas, es un tema con menor aparición en los debates metodológi-cos teóricos pero de gran relevancia para la transferibilidad de los resultados de los estudios realizados a un medio concreto a otros ámbitos [31][32][33][34] . La discusión se estructuró a partir de la valoración de dos aproximaciones en principio alternativas: la utilización de un repositorio de costes unitarios oficial y centralizado, por un lado, y la valoración específica por centro y/o comunidades autónomas (CCAA) en cada estudio, por otro.…”

Resource Modelling: The Missing Piece of the HTA Jigsaw?

“…This issue of transferability is not limited to resource modelling and has been identified as a significant barrier in HTA [35][36][37][38][39]. The applicability of resource modelling results to a given setting depends on the degree of variation between the settings in terms of diffusion, resource use and their associated constraints.…”