Generalized pustular psoriasis in a toddler with IL36RN mutation: a case report
Ghaith Adi,
Mohammed Rami Shaath,
Kareem Adi
et al.
Abstract:Generalized Pustular Psoriasis (GPP) is a dermatological autoinflammatory disease that rarely occurs in children and is associated with complex genetic factors. GPP pathogenesis has been associated with mutations in IL36RN gene, which encodes an interleukin-36 receptor antagonist. GPP usually occurs without a history of psoriasis in the patients or their family members. This case report describes the clinical course of a 3-year-old toddler with GPP. The diagnosis of GPP was confirmed through a comprehensive se… Show more
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