Generation and characterization of ionic and neutral cyanoisothiocyanate [NCNCS]+·/0 by neutralization - reionization mass spectrometry

Vivekananda, S.; Srinivas, R.

doi:10.1002/(sici)1097-0231(199712)11:18<1999::aid-rcm101>3.0.co;2-g

Cited by 3 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…), and m/z 26 (CN + , loss of H 2 CS). The peaks at m/z 44 and 45 are clearly in keeping with NCS connectivity12–16 rather than CNS connectivity, which is expected to give an abundant m/z 46 ion 20,21. The spectrum also shows two narrow peaks at m/z 36 and 35.5 corresponding to the doubly charged ions 72 ++ and a doubly charged hydrogen‐loss ion 71 ++ .…”

Section: Resultsmentioning

confidence: 72%

“…Earlier we reported the characterization of heterocumulenes such as thiocarbonylisothiocyanate [SCNCS],12 thiocarbonylisocyanate [SCNCO],13 cyanoisothiocyanate [NCNCS],14 iminothiosulfine [HCNCS 2 ],15 SiNCX [XO,S],16 and selenocumulene [HC 3 Se] 17. In continuation of our studies on heterocumulenes we focused our attention on ionic and neutral methyleneisothiocyanate, CH 2 NCS +/ .…”

mentioning

confidence: 99%

“…In continuation of our studies on heterocumulenes we focused our attention on ionic and neutral methyleneisothiocyanate, CH 2 NCS +/ . , which belongs to an interesting group of molecules for spectroscopic and theoretical studies because of the presence of the ambidentate NCS moiety 14. Tao et al .…”

mentioning

confidence: 99%

See 2 more Smart Citations

Molecular Drivers of Base Flipping During Sequence‐Specific DNA Methylation

Matje

Reich

2012

ChemBioChem

View full text Add to dashboard Cite

One step at a time: Substrates containing nucleotide analogues lacking sequence-specific contacts to the C5 methyltransferase M.HhaI were used to probe the role of individual interactions in effecting conformational transitions during base flipping. A segregation of duties, that is, specific recognition and chemomechanical force for base flipping and active site assembly, within the enzyme is confirmed.

show abstract

Section: Resultsmentioning

confidence: 72%

mentioning

confidence: 99%

See 1 more Smart Citation

Molecular Drivers of Base Flipping During Sequence‐Specific DNA Methylation

Matje

Reich

2012

ChemBioChem

View full text Add to dashboard Cite

show abstract

“…58,59 Later, they extensively used the neutralization/re-ionization mass spectrometry (NRMS) technique to characterize various ionic and neutral species in the gas phase. [60][61][62][63][64][65][66][67][68][69][70][71][72][73][74][75][76] In recent years, Srinivas and colleagues have been working on the application of ESI-tandem mass spectrometry (MS/ MS) to tert-butyloxycarbonyl (BOC)-protected peptides (two to eight amino acids) derived from non-natural amino acids such as sugar-substituted b-, g-(or) d-amino acids including hybrid peptides. [77][78][79][80][81][82][83][84][85][86][87][88][89][90][91][92] They have characterized these new peptides by fragmentation of protonated/sodiated species (sequencing) produced under positive (or) negative ESI and matrix-assited laser desorption/ionization (MALDI).…”

Section: Introductionmentioning

confidence: 99%

Mass Spectrometry in India

Vairamani

Prabhakar

2012

Eur J Mass Spectrom (Chichester)

View full text Add to dashboard Cite

All rights reserved EUROPEAN JOURNAL OF MASS SPECTROMETRY This review highlights the research in mass spectrometry carried out all over India, with a focus on the last two decades. There has been a phenomenal increase in the use of mass spectrometers in India during the last decade following the introduction, at the beginning of the 21st century, of rugged electrospray ionization sources for the commercially available instruments, with applications such as pharmacokinetics and bio-equivalence drug studies, pesticide residue analysis and proteomics. There have been more papers published in these areas than could be fully covered in this article. This review covers mostly research in mass spectrometry carried out continuously in institutions where advanced facilities for mass spectrometry are functional. Researchers in India, with some notable exceptions, have always used and still use commercial mass spectrometers in their various areas of research, rather than develop their unique instruments. The review is divided into three parts: organic, elemental (or atomic) and biological mass spectrometry. Organic mass spectrometry Organic and bio-organic chemistry Research in organic mass spectrometry in the early years was mainly focused on the study of mass spectral fragmentation of different classes of new compounds,and was initiated in the 1960s by the late Das and his colleagues from the National Chemical Laboratory (NCL), Pune. The first double-focusing mass spectrometer (CEC-110 B) was installed at NCL for high-resolution mass measurements. The compounds studied by Das and his colleagues included aromatic amides, Benzophenanthridine derivatives, norses

show abstract

Generation and characterization of ionic and neutral methylene isothiocyanate by a combined tandem mass spectrometry and computational study

Reddy

Rapole

Bhanuprakash

et al. 2004

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

The heterocumulene, methyleneisothiocyanate ion, CH2NCS+ (1a+), is generated by the dissociative electron ionization of 2‐mercaptoimidazole. This conclusion follows from tandem mass spectrometry experiments and theoretical calculations at the B3LYP/6‐311G** and G2/G2(MP2) levels. The calculations predict that 1a+ is separated by high energy barriers from its isomers CHNCHS (1b+), CHNCSH (1d+), CNCHSH (1e+) and CHNHCS (1f+). The low energy metastable ions 1a+ dissociate by loss of HCN via the pathway 1a+ → 1b+ → HCS+ + HCN. Neutralization‐reionization experiments confirm the theoretical prediction that the hitherto unknown heterocumulene CH2NCS. is a stable species in the rarefied gas phase. Copyright © 2004 John Wiley & Sons, Ltd.

show abstract

Generation and characterization of ionic and neutral cyanoisothiocyanate [NCNCS]+·/0 by neutralization - reionization mass spectrometry

Cited by 3 publications

References 4 publications

Molecular Drivers of Base Flipping During Sequence‐Specific DNA Methylation

Molecular Drivers of Base Flipping During Sequence‐Specific DNA Methylation

Mass Spectrometry in India

Generation and characterization of ionic and neutral methylene isothiocyanate by a combined tandem mass spectrometry and computational study

Contact Info

Product

Resources

About