2001
DOI: 10.1530/reprod/121.6.843
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Genes controlling ovulation rate in sheep

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Cited by 17 publications
(30 citation statements)
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“…Indeed a recent report shows that ALK5 (TGFβRI) is the type 1 receptor for GDF9 [19]. This finding suggests that GDF9 could have autocrine effects on the oocyte from the type 1 stage and paracrine effects on both the granulosa and theca cells from the type 4 (range [20]. S31 preantral) stage of growth.…”
Section: Intraovarian Sites Of Bmp15 and Gdf9 Gene Expression And Posmentioning
confidence: 96%
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“…Indeed a recent report shows that ALK5 (TGFβRI) is the type 1 receptor for GDF9 [19]. This finding suggests that GDF9 could have autocrine effects on the oocyte from the type 1 stage and paracrine effects on both the granulosa and theca cells from the type 4 (range [20]. S31 preantral) stage of growth.…”
Section: Intraovarian Sites Of Bmp15 and Gdf9 Gene Expression And Posmentioning
confidence: 96%
“…Q249R) in a highly conserved region of the intra cellular kinase domain [23,28,33]. The dominant phenotype is precocious ovarian follicular development [20] and exceptional prolificacy [4]. Some significant secondary effects have been observed in Booroola sheep, most likely because ALK6 mRNA is present in a wide range of tissues as well as the ovaries, including the brain, pituitary, kidneys, skeletal muscle, uterus and prostate and testes [20,33].…”
Section: The Alk6 (Bmpr-ib) Mutationmentioning
confidence: 99%
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“…Correspondingly, breeding schemes for improved lamb-meat production have focused on selecting animals with superior reproductive capacities, and studies directed at the genetic improvement of sheep have been primarily concerned with reproductive traits (for review, see [45]). From a producer's standpoint, a greater number of lambs result in a higher profit margin.…”
Section: Introductionmentioning
confidence: 99%