Genetic amniocentesis in multiple gestations

Abstract

Thirty-one genetic amniocenteses involving multiple gestations were performed in the genetics unit between 1976 and 1982. Three sets of triplets were included. Precise locations of the sacs were determined using real-time ultrasonography and successful sampling of all sacs was accomplished. Spontaneous abortions occurred in two normal twins and one normal triplet gestation. Two therapeutic abortions were performed for fetal abnormalities. Two cases of discordance for trisomy 21 (one twin and one triplet) were allowed to continue; the twin case terminated at 25 weeks' gestation with neonatal deaths and the triplets are alive and well.

Second‐trimester amniocentesis vs. chorionic villus sampling for prenatal diagnosis in multiple gestations

“…A detailed ultrasound scan was performed prior to the procedure with a 3.5-MHz sector or a 3.75-MHz curvilinear transducer, to determine the number of fetuses and the placental and cord Correspondence: Dr A. Souka,27 Koletti str, 152-36, Athens, Greece (e-mail: athena@spark.net.gr) Amniocentesis and chorionic villus sampling in multiple gestations Antsaklis et al locations and to assess fetal growth and anatomy. In firsttrimester scans chorionicity was determined based on the presence of the lambda sign 8 .…”

Second trimester amniocentesis in assisted conception versus spontaneously conceived twins

“…Many studies have reported on the pregnancy loss rate after amniocentesis in twins (11)(12)(13)(14)(15)(16)(17)(18). However, there are no data concerning the risk of the procedure in twins conceived after ART.…”

Second trimester amniocentesis in twin pregnancies: maternal haemoglobin as a dye marker to differentiate diamniotic twins

“…In one case, this was probably the result of polyhydramnios, making the fetal loss due to amniocentesis 24%. The reported rates of miscarriage after mid‐trimester amniocentesis in twin pregnancies differ greatly, but even 4% is not unusually high (Elias et al 1980; Palle et al 1983; Librach et al 1984; Filkins et al 1984; Pijpers et al 1988). There was no perinatal mortality.…”