2024
DOI: 10.21203/rs.3.rs-3791588/v1
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Genetic analyses point to alterations in immune-related pathways underpinning the association between psychiatric disorders and COVID-19

Anna Monistrol-Mula,
Santiago Diaz-Torres,
Mireia Felez-Nobrega
et al.

Abstract: Current literature suggests that people with psychiatric disorders have higher risk of SARS-CoV-2 infection and a worse prognosis of the disease. We aimed to study the genetic contribution to these associations in a range of psychiatric disorders and COVID-19, and determine whether these are unique or shared across psychiatric disorders. Using the largest available genome-wide association studies, we analysed the genetic overlap between six psychiatric disorders and COVID-19. We further identified specific reg… Show more

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