Genetic features of sensitivity to vitamin D and prevalence of vitamin D deficiency among outpatients

Poluektova, A.Yu.; Martynova, Evgenia; Fatkhutdinov, I.R.; Demidova, T. Yu.; Poteshkin, Yury

doi:10.32364/2618-8430-2018-1-1-11-17

Cited by 4 publications

(2 citation statements)

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“…По ее результатам, оптимальная концентрация витамина D выявлена у 38% пациентов (n=213); (39,7±9,6 нг/мл), дефицит витамина D — у 25% (n=141); (16,2±3,4 нг/мл), а недостаточность — у 37% (n=211); (24,9±2,5 нг/мл). Таким образом, у 62% пациентов отмечается низкий уровень витамина D [ 26 ], что на 24,67% ниже в сравнении с данными, полученными по Москве в настоящем исследовании (86,67%). При анализе опубликованного материала исследователей из северо-западного региона РФ, где уровень обеспеченности витамином D изучался среди 1569 жителей г. Санкт-Петербурга и г. Петрозаводска, было отмечено, что показатели недостаточности и дефицита витамина D встречаются чрезвычайно часто — в 83,2% [ 27 ] случаев, что практически сопоставимо с проведенным исследованием, где эта цифра достигла 91,49%.…”

Section: Discussionunclassified

Vitamin D deficiency in Russia: the first results of a registered, non-interventional study of the frequency of vitamin D deficiency and insufficiency in various geographic regions of the country

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Pigarova

Rozhinskaya

et al. 2021

Probl Endokrinol (Mosk)

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BACKGROUND. In Russian Federation, there are no large-scale cross-sectional multicenter epidemiological studies assessing the prevalence of vitamin D deficiency and insufficiency in different geographical latitudes. Insufficient solar insolation and inadequate vitamin D content in food dictate the need to study the epidemiological structure of low vitamin D status in Russia.AIM. To assess the incidence of vitamin D deficiency and insufficiency among the population living in the regions of the Russian Federation located at latitudes from 45 ° to 70 °.MATERIALS AND METHODS. The first stage of the Russian multicenter non-interventional registry study using the «crosssectional» method was carried out from March 2020 to May 2020.RESULTS. In regions that represent a geographically representative sample of regions of the Russian Federation with a high risk of developing low levels of vitamin D, it’s deficiency was noted in 55.96%, and the level of deficiency and insufficiency was recorded in 84.01%.CONCLUSION. Close attention to the wide scale of the problem of vitamin D deficiency and insufficiency in the Russian Federation will contribute to the progressive formation of various educational and preventive programs necessary to strengthen health and improve the quality of life of the population.

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Section: Discussionunclassified

Vitamin D deficiency in Russia: the first results of a registered, non-interventional study of the frequency of vitamin D deficiency and insufficiency in various geographic regions of the country

Суплотова

Pigarova

Rozhinskaya

et al. 2021

Probl Endokrinol (Mosk)

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“…Анализируя уровень витамина D в г. Архангельске, установлено, что 74% взрослого населения имеют уровень витамина D менее 30 нг/мл [17]. Также по результатам многих других эпидемиологических исследований [18][19][20][21][22], проводимых на территории Российской Федерации (РФ), отмечено, что сниженная концентрация витамина D в сыворотке крови имеет место у 50-92% взрослого населения трудоспособного возраста. К причинам возникновения D-дефицита относят множество факторов [23]: географическое расположение территории, климатические и погодные условия, интенсивность солнечной инсоляции и общее количество солнечных дней, а также особенности питания, избыточный вес, наличие ряда патологических состояний, прием некоторых медикаментозных веществ [24,25] Вместе с этим при изучении связи антропометрических данных участников исследования с уровнем 25(OH) D отмечается отчетливая взаимосвязь содержания витамина D в сыворотке крови с ИМТ, ОТ и массой тела обследованных (р<0,05).…”

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Vitamin D status in residents of Tyumen region

et al. 2019

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BACKGROUND: The high prevalence of vitamin D deficiency worldwide is often associated with the region of residence. AIMS: to study the level of vitamin D in serum of residents living in Tyumen region, to assess the frequency of occurrence of insufficiency and deficiency of vitamin D in the region. MATERIALS AND METHODS: Observational, single-site, transverse, selective, uncontrolled study of the prevalence of vitamin D deficiency among adults in Tyumen region, conducted from November 2017 to March 2018. RESULTS: Optimal levels of 25(OH)D in the residents of the Tyumen region were found in 7.3% of patients, its insufficiency was registered in 22.0% of cases, and defficiency in 70.7%. There was a weak correlation relationship between lower values of 25(OH)D in those examined with obesity according to body mass index (r = -0.104, p 0.05) and waist circumference (r = -0.239, p 0.05), and with greater body mass (r = -0.130, p 0.05). CONCLUSIONS: There is a high prevalence of insufficiency and deficiency of vitamin D among the adult population living in Tyumen region has been revealed. Additionally, it has been established that the level of vitamin D is not associated with gender and age, but is associated with BMI, waist circumference and body weight of patients.

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