Genetic Predisposition to Anticonvulsant Hypersensitivity

Pirmohamed, Munir

doi:10.1002/cpt.1610

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Precision Medicine In Clinical Pharmacology1

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Cited by 2 publications

(1 citation statement)

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“…As Pirmohamed describes, one of the best studied and well‐known pharmacogenomics findings is the association between carbamazepine‐induced severe reactions and certain HLA variants (i.e., HLA‐B*15:02 and HLA‐A*31:01). He further shows the path to the future of pharmacogenomics in the prevention of immune‐related adverse drug reactions.…”

Section: Precision Medicine In Clinical Pharmacologymentioning

confidence: 99%

The Future of Precision Medicine

Verstegen

Itô

2019

Clin Pharma and Therapeutics

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Precision medicine is an emerging framework to maximize therapeutic benefit by modifying the treatment for individual patients based on their variations in demographic, genomic, and environmental factors. In particular, “Pharmacogenomics” and “Therapeutic Drug Monitoring” are key elements of individualized drug treatment, staging Clinical Pharmacology at the forefront of precision medicine.

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Section: Precision Medicine In Clinical Pharmacologymentioning

confidence: 99%