Genetic predisposition to helminthiasis

Abstract

Helminthes accompany human beings from the early period of the formation, there is a long-term coevolution between parasite and human, helminthes represent a major selective force for human immune genes. Data on genetic control of the intensity and clinical traits of helminthinfection in different populations, including results obtained by whole-genome studies are presented and concept of common genes of susceptibility to helminth infection and allergic diseases are discussed.