Genetic Transformation for Metabolic Engineering of Tropane Alkaloids

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“…Metabolic engineering to increase secondary metabolites can be performed in different ways. These include the overexpression of certain genes to regulate metabolic pathways (Alvarez and Marconi, 2011). Similarly, Lu et al (2016) stated that overexpressing genes in the terpenoid biosynthetic pathway in homologous and ectopic plants provided a reliable method for increasing terpenoids.…”

Overexpression of 3-hydroxy-3-methylglutaryl Eoenzyme-A reductase-1 (HMGR1) Enhanced andrographolide Accumulation in Andrographis paniculata (Burm.F.)

“…Metabolic engineering to increase secondary metabolites can be performed in different ways. These include the overexpression of certain genes to regulate metabolic pathways (Alvarez and Marconi, 2011). Similarly, Lu et al (2016) stated that overexpressing genes in the terpenoid biosynthetic pathway in homologous and ectopic plants provided a reliable method for increasing terpenoids.…”