2020
DOI: 10.1371/journal.pone.0233254
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Genetic variation associated with PPO-inhibiting herbicide tolerance in sorghum

Abstract: Herbicide application is crucial for weed management in most crop production systems, but for sorghum herbicide options are limited. Sorghum is sensitive to residual protoporphyrinogen oxidase (PPO)-inhibiting herbicides, such as fomesafen, and a long re-entry period is required before sorghum can be planted after its application. Improving sorghum for tolerance to such residual herbicides would allow for increased sorghum production and the expansion of herbicide options for growers. In this study, we observe… Show more

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Cited by 6 publications
(4 citation statements)
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“…A tolerância encontrada no BAF88 pode estar relacionada à capacidade de detoxificação, rápida metabolização, redução da absorção e translocação, sequestro, aumento da atividade de enzimas antioxidantes, variação e mutação gênica, que são importantes mecanismos de tolerância das plantas aos herbicidas (Powles & Yu, 2010;Busi et al, 2018;Adhikari et al, 2020;Moore et al, 2022). Também os genótipos de feijão avaliados responderam de forma diferente aos efeitos provocados pelos herbicidas, sendo observado maior tolerância para BAF88, permitindo inferir que há variabilidade na tolerância dos genótipos de feijão ao herbicida S-metolachlor.…”
Section: Resultsunclassified
“…A tolerância encontrada no BAF88 pode estar relacionada à capacidade de detoxificação, rápida metabolização, redução da absorção e translocação, sequestro, aumento da atividade de enzimas antioxidantes, variação e mutação gênica, que são importantes mecanismos de tolerância das plantas aos herbicidas (Powles & Yu, 2010;Busi et al, 2018;Adhikari et al, 2020;Moore et al, 2022). Também os genótipos de feijão avaliados responderam de forma diferente aos efeitos provocados pelos herbicidas, sendo observado maior tolerância para BAF88, permitindo inferir que há variabilidade na tolerância dos genótipos de feijão ao herbicida S-metolachlor.…”
Section: Resultsunclassified
“…It is striking that PPO-R is, with a high frequency, associated with resistance to herbicides with other MoAs (i.e., multiple-resistant cases) (Table 2). This might be due to: (1) the use of different herbicides in sequence or mixtures and independent evolution of resistance to compounds of each MoA; (2) the evolution of unspecific non–target site resistance (NTSR), such as metabolic resistance, conferring resistance to a broad range of different herbicide chemistries inhibiting different targets (Adhikari et al 2020; Comont et al 2020; Han et al 2021); or (3) a combination of both mechanisms. It is worth noticing that 29 cases of the 40 described are multiresistant, with 7 cases resistant to five or more MoAs (Table 3).…”
Section: History and Distribution Of Ppo-resistant Weedsmentioning
confidence: 99%
“…Researchers can use Genome-Wide Association Studies (GWAS) to associate mutations in genetic elements to key traits for improved weed management, such as herbicide tolerance or those that allow crops to outcompete weeds. This strategy has been successfully applied to crop species such as wheat ( Shi et al, 2020 ; Xu et al, 2020 ), cotton ( Thyssen et al, 2014 , 2018 ), sorghum ( Adhikari et al, 2020 ), and fababean ( Abou-Khater et al, 2022 ) for varied natural herbicide tolerance.…”
Section: Potential Molecular Approaches Targeting Weeds To Control Fi...mentioning
confidence: 99%