Abstract:Introduction: Children with various genetic backgrounds, including those carrying the NPHS2 gene, which encodes the protein podocin necessary for the maintenance of the glomerular permeability barrier, are more likely to develop idiopathic nephrotic syndrome (INS), which is the most prevalent glomerular disease. Variations in this gene may influence the prognosis and steroid responsiveness in children with INS. Aim of the study: Our objective was to investigate the association of NPHS2 genetic variants rs61747… Show more
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