Genetically Engineered Cellular Nanovesicles: Theories, Design and Perspective
Qinzhen Cheng,
Runtan Li,
Yiling He
et al.
Abstract:The use of cellular nanovesicles (CNVs) is a groundbreaking innovation in biomedical applications. Both natural extracellular vesicles (EVs) and artificial cell membrane nanovesicles (AVs) have emerged as innovative CNVs, but they have limitations in therapeutic effects and targeting abilities. Challenges such as stability, immunogenicity, and drug payload capacity hinder their widespread application. Genetic engineering has matured as a widely employed modification strategy, leading to the development of gene… Show more
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