Genomic survey maps differences in the molecular complement of vesicle formation machinery between Giardia intestinalis assemblages
Shweta V. Pipaliya,
Joel B. Dacks,
Matthew A. Croxen
Abstract:Giardia intestinalis is a globally important microbial pathogen with considerable public health, agricultural, and economic burden. Genome sequencing and comparative analyses have elucidated G. intestinalis to be a taxonomically diverse species consisting of at least eight different sub-types (assemblages A-H) that can infect a great variety of animal hosts, including humans. The best studied of these are assemblages A and B which have a broad host range and have zoonotic transmissibility towards humans where … Show more
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