Genotoxicity and oxidative damage in zebrafish (Danio rerio) after exposure to effluent from ethyl alcohol industry

Derikvandy, Azam; Pourkhabbaz, Hamid Reza; Banaee, Mahdi; Sureda, Antoni; Haghi, Nematdoost; Pourkhabbaz, Alireza

doi:10.1016/j.chemosphere.2020.126609

Cited by 43 publications

(15 citation statements)

References 71 publications

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“…Also, porins can signi cantly affect cellular biochemical homeostasis by disrupting the selective permeability of cell membranes (Portnyagina, et al, 2021). ALP is a transmembrane metalloenzyme involved in protein phosphorylation, cell growth, apoptosis, and cell migration (Derikvandy, et al, 2020).…”

Section: Resultsmentioning

confidence: 99%

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Toxicity Effects of Microplastics Individually and in Combination the Fish Pathogen Yersinia Ruckeri on the Rainbow Trout (Oncorhynchus Mykiss)

Banihashemi

Soltanian

Gholamhosseini

et al. 2021

Preprint

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Exposure to xenobiotics such as Yersinia ruckeri can significantly affect bacterial infections in fish. Microplastics (MPs) may predispose fish to infection and act as carriers in pathogen transmission. Therefore, this study is designed to evaluate MPs' effect on damage caused by exposure to Y. ruckeri in rainbow trout. In this study, blood biochemical parameters and hepatic oxidative biomarkers as clinical signs were measured in the fish co-exposed to Y. ruckeri (5 and 10% LD50) and MPs (500 and 1000 mg Kg-1) for 30 days. There were no significant changes in the creatinine, triglyceride, cholesterol levels, and glutamic-pyruvic transaminase activity in the blood of fish infected with Y. ruckeri. In contrast, exposure to MPs had a significant effect on most clinical parameters. The total protein, albumin, globulin, total immunoglobulins, High-density lipoprotein, low-density lipoprotein, cholesterol levels, and γ-glutamyltransferase activity decreased, whereas glucose, triglyceride, and creatinine levels, and glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase, alkaline phosphatase, and lactate dehydrogenase activities increased in the plasma of fish after co-exposure to MPs and Y. ruckeri. Dietary MPs combined with a bacterial challenge decreased catalase activities, glutathione peroxidase, and total antioxidant levels. However, the superoxide dismutase activity and malondialdehyde contents in the hepatocytes increased in the hepatocyte of fish co-exposed to MPs and Y. ruckeri. In conclusion, this study showed that fish exposure to MPs and simultaneous challenge with Y. ruckeri could have a synergistic effect on clinical parameters.

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Section: Resultsmentioning

confidence: 99%

“…In the present study, the following mathematical models were used to predict the interaction of MPs and Y. ruckeri on each other. According to Banaee et al (2020), the synergism rate is calculated only when the predicted effect is higher than the observed one.…”

Section: Assessment Of Synergism and Antagonismmentioning

confidence: 99%

Toxicity Effects of Microplastics Individually and in Combination the Fish Pathogen Yersinia Ruckeri on the Rainbow Trout (Oncorhynchus Mykiss)

Banihashemi

Soltanian

Gholamhosseini

et al. 2021

Preprint

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“…Oxidative stress indicators are suitable biomarkers for evaluating chemical compounds’ cytotoxicity (Banaee et al, 2019; Derikvandy et al, 2020; Ibrahim et al, 2021). Although most reports have been referred to the protective properties of methylene blue against oxidative stress (Aksu et al, 2010; Yildiz et al, 2011), methylene blue, like other veterinary drugs, may lead to long‐term cytotoxicity.…”

Section: Discussionmentioning

confidence: 99%

Effects of exposure to a therapeutic level of methylene blue on antioxidant capacity, haemato‐immunological responses and resistance of goldfish,Carassius auratustoAeromonas hydrophila

Soltanian

Gholamhosseini

Banaee³

2021

Aquaculture Research

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Methylene blue (MB) can have inhibitory effects against protozoan and fungi in fish. In this investigation, fish were first exposed to different MB concentrations (0 and 2 mg L−1) for 21 days. Then, the fish were challenged with Aeromonas hydrophila for 7 days. Some haemato‐immunological and biochemical parameters, oxidative stress biomarkers in blood, growth performance and fish resistance to A. hydrophila were examined once a week. The results showed that erythrocyte, haemoglobin, leucocytes, haematocrit, mean corpuscular volume., mean corpuscular haemoglobin concentration and lymphocyte percentage significantly reduced in the fish after exposure to 2 mg L−1 MB on the 14th and 21st days and challenged period on 28th day. Although the superoxide dismutase, catalase, and glutathione peroxidase, lysozyme, phagocytic activities and a quantitative nitroblue tetrazolium, total protein and cellular total antioxidant levels in the serum decreased significantly, the percentage of neutrophils, aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase activities increased significantly in fish exposed to 2 mg L−1 MB (p < 0.05). There was a significant difference in the growth performance and the percentage of monocytes exposed to 2 mg L−1 of MB compared to the reference group. The mortality rate was declined in the treated fish with 2 mg L−1 of BM after challenge with A. hydrophila compared with the control group. Overall, the present results indicate some negative impacts of MB application in goldfish even at the therapeutic level. From these, the immunosuppressive effects of MB may be potentially disruptive for a health condition.

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“…The natural aquatic ecosystems usually contain various xenobiotics that can affect fish [14,15]. In other words, fish may live in the cocktails of different pollutants [16,17].…”

Section: Interaction Of Herbicides With Other Xenobioticsmentioning

confidence: 99%

“…Damage to membrane phospholipids decreases the cellular chance of survival and increases apoptosis and necrosis rates. Disruption in the cellular membrane's physiological function also affects metabolism, biochemical hemostasis, gene expression, and DNA replication in the cells [15]. In the following, we want to explain the effects of herbicides on aquatic animals in more detail.…”

Section: Detoxification and Metabolism Of Herbicidesmentioning

confidence: 99%

Toxicological Interaction Effects of Herbicides and the Environmental Pollutants on Aquatic Organisms

Banaee¹

2023

New Insights in Herbicide Science

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Although herbicides are designed to remove or control weeds, pollution of water ecosystems with herbicides could have adverse effects on aquatic animals such as fish. The effect of herbicides on nontarget organisms may be different than expected, as herbicides may interact with another environmental contaminant. Since there are different contaminants in the water, fish may live in the cocktail of xenobiotics, including herbicides. Therefore, herbicides alone and in combination with other pollutants could affect fish physiology. Thus, the interaction of environmental contaminants with pesticides may create a situation in which a chemical affects the activity of a pesticide; that is, its effects increase or decrease or produce a new effect that neither of them creates on its own. These interactions may occur due to accidental misuse or lack of knowledge about the active ingredients in the relevant materials. This study aimed to review the effects of herbicides alone and in combination with other xenobiotics on various aspects of fish biology. In this study, different biomarkers were reviewed in fish exposed to herbicides.

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Genotoxicity and oxidative damage in zebrafish (Danio rerio) after exposure to effluent from ethyl alcohol industry

Cited by 43 publications

References 71 publications

Toxicity Effects of Microplastics Individually and in Combination the Fish Pathogen Yersinia Ruckeri on the Rainbow Trout (Oncorhynchus Mykiss)

Toxicity Effects of Microplastics Individually and in Combination the Fish Pathogen Yersinia Ruckeri on the Rainbow Trout (Oncorhynchus Mykiss)

Effects of exposure to a therapeutic level of methylene blue on antioxidant capacity, haemato‐immunological responses and resistance of goldfish,Carassius auratustoAeromonas hydrophila

Toxicological Interaction Effects of Herbicides and the Environmental Pollutants on Aquatic Organisms

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