2009
DOI: 10.1016/j.tiv.2009.05.025
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Genotoxicity evaluation of locally produced dental porcelain – An in vitro study using the Ames and Comet assays

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Cited by 18 publications
(16 citation statements)
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“…The same has been observed by others authors using in vitro genotoxicity tests of different ceramic compounds. For instance, Noushad et al29 investigating a dental porcelain, observed that these materials have no genotoxic potential when cultured with fibroblastic cells after 24 h. Ribeiro et al30 tested a mineral trioxide aggregate in cultured mouse lymphoma cells for a period of 3 h. The authors also evidenced that these materials do not have genotoxic potential, corroborating with the findings of this study.…”
Section: Discussionsupporting
confidence: 84%
“…The same has been observed by others authors using in vitro genotoxicity tests of different ceramic compounds. For instance, Noushad et al29 investigating a dental porcelain, observed that these materials have no genotoxic potential when cultured with fibroblastic cells after 24 h. Ribeiro et al30 tested a mineral trioxide aggregate in cultured mouse lymphoma cells for a period of 3 h. The authors also evidenced that these materials do not have genotoxic potential, corroborating with the findings of this study.…”
Section: Discussionsupporting
confidence: 84%
“…These biomaterials are in close contact with soft and hard oral tissues; therefore, an important feature of these biomaterials must be the ability to coexist in contact with tissues without causing any irritating, inflammatory, allergic, toxic, or carcinogenic reactions [1][2][3][4][5]. Surface roughness (SR) of dental materials might cause microtraumas in the tissue and enhance microorganism's retention, contributing directly or indirectly to promote tissues injury and to increase the incidence of oral disease [6][7][8].…”
Section: Introductionmentioning
confidence: 99%
“…The preservations of mouse fibroblast cell line L929 cells and human arterial endothelial cells (HAECs) were investigated. Both fibroblast cells and endothelial cells are widely used as model cells in many biology studies, especially toxin screenings and tissue engineering 26, 27. In the chamber, L929 cells dispersed inside the hydrogel and exhibited round geometry after encapsulation ( Figure ).…”
mentioning
confidence: 99%