“…Statistical compression methods utilize statistical models to achieve compression [9], [12]. Dictionary-based compression methods use a dictionary of sequences to replace repeated sequences in the data [13], [14], [15], [16]. Reference-based compression, on the other hand, leverages the high interredundancy between chromosomes of the same species by storing the differences between the original sequence and a suitable reference sequence [17], [18], [19], [20], [21], [22].…”