Gentian violet: Revisited

Abstract

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Gentian Violet Inhibits Cell Proliferation through Induction of Apoptosis in Ovarian Cancer Cells

“…The other mode of action is induction of microbial cell death via formation of a covalent adduct with thioredoxin reductase 2. Currently, based on these effects, studies on the treatment of skin diseases caused by microbial infections and studies on its anti-angiogenic and antitumor effects are being reported [ 13 , 14 ]. Several studies have demonstrated the anticancer effect of GV.…”

“…In addition, GV is also used for bacterial cell staining to distinguish between Gram-positive and -negative bacteria. Currently, GV is being studied as a treatment for skin diseases and as an anti-angiogenic and antitumor drug [ 13 , 14 ]. Studies have demonstrated the anticancer effects of GV in several cancer cells; however, its anticancer effects have not yet been demonstrated in OC cells [ 15 , 16 , 17 , 18 , 19 ].…”

Avaliação ex vivo da coloração da cápsula anterior da lente de cavalos com três concentrações de violeta genciana para treinamento cirúrgico

“…O violeta genciana é um corante com uma extensa e diversificada história como agente medicinal (24,25) , principalmente devido sua ação antisséptica (26) . Na oftalmologia, há relatos de seu uso como marcador de córnea, conjuntiva e cápsula anterior da lente (11) .…”

Enhanced strategy against mediastinitis with thoracic vascular graft infection: A combination of hydro‐debridement with pulsed lavage and negative pressure wound therapies

“…13 Although no report of the carcinogenesis in humans associated with topical use of gentian violet has been found in the recent literature, gentian violet is considered as a potential carcinogen. 16 Gentian violet should be limited to short-term external use to ensure a minimal possibility of cancer development. We expected these efficacies in using a saline solution containing gentian violet of 0.0005% for pulsed lavage in all patients.…”

“…Gentian violet is characterized by rare local chemical irritation and bacterial growth inhibition caused by deposition on necrotic tissues 13 . Although no report of the carcinogenesis in humans associated with topical use of gentian violet has been found in the recent literature, gentian violet is considered as a potential carcinogen 16 . Gentian violet should be limited to short‐term external use to ensure a minimal possibility of cancer development.…”