––We carried out a detailed geological, geochronological, geochemical, and isotope study of diorites from a dike located in the central part of the Baikal uplift of the Siberian craton. The geochemical and isotope data obtained for diorites of the studied intrusion were compared with coeval mafic and intermediate igneous rocks of the southern part of the Siberian craton. The U–Pb (ID-TIMS) baddeleyite age of 1862 ± 7 Ma has been estimated for diorite from a dike located in the area of the Onguren Village. The obtained data are the first reliable age determination for the Paleoproterozoic mafic and intermediate igneous rocks of the Baikal uplift, which are part of the South Siberian postcollisional magmatic belt. The dike is of NE strike. The dike rocks correspond in chemical composition to diorites and are highly differentiated varieties (mg# = 36.5–37.4). There are no significant variations in the composition of diorites in the marginal and central parts of the dike. The rocks are characterized by low contents of TiO2, P2O5, and Nb, high contents of Th, Zr, Ba, and LREE, and low negative values of εNd(T) (–5.9 to –6.2). We assume that the diorites formed from the enriched subcontinental lithospheric mantle. The obtained geochemical and isotope data show similar negative values of εNd(T) from –4.3 to –11.6 for most of Paleoproterozoic mafic and intermediate igneous rocks of the South Siberian postcollisional magmatic belt within the Aldan Shield, the Baikal uplift, and the Irkut block of the Sharyzhalgai uplift. These rocks correspond in geochemical features to rocks resulted from the melting of subduction-modified lithospheric mantle sources in the postcollisional extension setting at the final Paleoproterozoic stage of formation of the Siberian craton.