Gestational trophoblastic disease: one more risk in adolescent pregnancy

Abstract

Adolescents comprise approximately 20% of all gestational trophoblastic disease patients and have high adhesion to follow up. The disease did not affect their reproductive capacity, and chances of a normal subsequent gestation were high.

Emotional and Clinical Aspects Observed in Women with Gestational Trophoblastic Disease: A Multidisciplinary Action

“…GTD was diagnosed using the 2002 International Federation of Gynecology and Obstetrics (FIGO) criteria: hCG concentrations plateaued at values greater than or equal to 10%, hCG rise of more than 10% for three consecutive weeks, or histological diagnosis of choriocarcinoma. 18 19 …”

“…GTD was diagnosed using the 2002 International Federation of Gynecology and Obstetrics (FIGO) criteria: hCG concentrations plateaued at values greater than or equal to 10%, hCG rise of more than 10% for three consecutive weeks, or histological diagnosis of choriocarcinoma. 18,19 Clinical staging of women that progressed to GTN used the 2002 FIGO-World Health Organization (WHO) criteria. Their risk score at the time of GTN diagnosis and beginning of the treatment indicated the most adequate type of management considering the risk of developing resistance to chemotherapy: single-agent chemotherapy when the risk score was lower than or equal to 6, and multi-agent chemotherapy if the score was greater than 7.…”

“…Fear of the unknown --------------------------------------------------------------------Several studies have reported on the relevance of the impact of communications, treatment and emotional support received from a multidisciplinary team. 6,17,18,20 The perceptions of women with GTD have also been evaluated using questionnaires, such as the Health-Related Quality Of Life and the Patient Reported Outcome Measures (PROM), which cover several domains, such as physical effects, emotional symptoms (anxiety, depression) and social relationships. Psychological interventions, participation in a SG and participation of the family, when combined with continuous education about their disease, play an important role in the context of the treatment by a multidisciplinary team.…”

Gestational trophoblastic disease a contemporary review of diagnostic and pathology. Current challenge and future directions for gynecologists and obstetricians

“…However, the occurrence of the disease does not affect the reproductive capacity of female patients. [ [17][18][19] Complete and partial moles have been classified as two separate disease entities, and their division depends on the genetic material they contain. The complete mole has a complete set of chromosomes coming only from the paternal genome, while the partial mole is triploid and the genetic material transferred comes from the father and mother.…”

Complete molar pregnancy in adolescents from North and South America: Clinical presentation and risk of gestational trophoblastic neoplasia

“…Although advanced maternal age is associated with a higher risk for molar pregnancy, HM patients N 40 years represent 4.5-5% [4,6], whereas adolescents with HM account for 10-34% of the cases in large trophoblastic diseases referral centers [5,[7][8][9].…”