Gewerbliche Vergiftungen

Polychlorinated naphthalene exposures and liver function changes

“…Our conclusions are supported by reports such as that of von Wedel et al [1943]. Other investigators reported liver toxicity of PCNs without occurrence of chloracne [Cotter, 1944;Collier, 1943;Teleky, 1955]. It has been shown that PCNs (Halowax 1014) produce long-lasting oxidative stress in rat livers [Mäntylä and Ahotupa, 1993].…”

Persistent Mercury in Nerve Cells 16 Years After Metallic Mercury Poisoning

“…Poisoning by inorganic mercury in the majority of cases is considered to be reversible on removal from the source of intoxication (Hunter, 1959) but in severely affected cases the symptoms and signs of mercurialism may persist (Teleky, 1955;Takahata et al, 1970). In the few reported cases studied postmortem, no significant structural changes have been noted (Brigatti, 1949) with the exception of the unique cases of chronic calomel poisoning reported by Davis et al (1974).…”

Chlorinated naphthalenes [MAK Value Documentation, 1999]

“…After repeated exposure to chlorinated naphthalenes, liver damage such as acute liver necrosis, hepatitis and jaundice, and skin damage and chlorine acne were found in workers (ACGIH 1992c, Collier 1943, Cotter 1944, Crow 1970, Drinker et al 1937, Greenburg et al 1939, Jones 1941, Strauss 1944, Sulzberger et al 1934, Teleky 1927, 1955, von Wedel et al 1943. However, liver damage and chlorine acne also occur independently (Collier 1943, Cotter 1944, Drinker et al 1937, Kleinfeld et al 1972, Teleky 1955. In individual cases, liver damage was observed after as little as 7 weeks exposure (Teleky 1955).…”

“…However, liver damage and chlorine acne also occur independently (Collier 1943, Cotter 1944, Drinker et al 1937, Kleinfeld et al 1972, Teleky 1955. In individual cases, liver damage was observed after as little as 7 weeks exposure (Teleky 1955). A case of hepatitis was reported in a factory in which trichloronaphthalene concentrations of about 3 mg/m 3 were measured (Mayers and Smith 1942).…”