1972
DOI: 10.1002/jps.2600611015
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GI Absorption of two Crystal Forms of Sulfameter in Man

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Cited by 30 publications
(41 citation statements)
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“…Thus, in view of the current emphasis on understanding molecular mechanism in terms of spatial arrangement of component atoms of the ligands in the vicinity of the receptors (3,4), it is imperative that information on molecular properties of the toxins and xenobiotics is invariably given while describing their biologic activity. The two forms of lantadene A might differ in their bioavailability similar to observations on bioavailability for drugs such as chloramphenicol, sulfonamides, and aspirin (13, 24,31,32). The molecular aspects of gastrointestinal biotransformation, if any, and of the uptake and transport of lantadene A are not yet known.…”
Section: Discussionmentioning
confidence: 68%
“…Thus, in view of the current emphasis on understanding molecular mechanism in terms of spatial arrangement of component atoms of the ligands in the vicinity of the receptors (3,4), it is imperative that information on molecular properties of the toxins and xenobiotics is invariably given while describing their biologic activity. The two forms of lantadene A might differ in their bioavailability similar to observations on bioavailability for drugs such as chloramphenicol, sulfonamides, and aspirin (13, 24,31,32). The molecular aspects of gastrointestinal biotransformation, if any, and of the uptake and transport of lantadene A are not yet known.…”
Section: Discussionmentioning
confidence: 68%
“…1,3,4) In addition, the relative thermodynamic stability of the polymorphs has also been of great interest. Polymorphs fall into one of two categories: a monotropic system or an enantiotropic system.…”
mentioning
confidence: 99%
“…For primary structural characterization of individual components used for preparing MBFs the 13 C CP/MAS NMR spectra were measured (Figure 1). Signal assignment was performed on the basis of our experience and 13 C CPPI/MAS NMR experiments. As indicated by the relatively small linewidths of the signals of neat CPX (ca.…”
Section: ■ Materials and Methodsmentioning
confidence: 99%