Giant Cell Myocarditis: Case Review

Abstract

Introduction: Although giant cell myocarditis (GCM) is a rare, potentially fatal disease but its true prevalence is likely to be underestimated. GCM can lead to progressive heart failure, fatal ventricular arrhythmia and atrio-ventricular block. Case Presentation: The present report describes three cases of biopsy-proven GCM with clinical presentation including arrhythmia and heart failure. All patients were treated with immunosuppressant drugs. Conclusions: Arrhythmia and symptoms of heart failure with immunosuppression had a relative improvement in three patients.