Giant Dural Supratentorial Chondroma Generating the Question of How Large Can a Tumor Become without Revealing Itself

Abstract

Chondromas usually affect the small bones of hand and feet and account for only 0.5% of all intracranial tumors. We present a case of a giant, supratentorial meningeal chondroma in a 19-year old male patient and discuss the preoperative diagnostic findings as well as the appropriate treatment options. A 19-old male presented with headache, new onset of focal seizures and paresis of left upper extremity. Magnetic resonance imaging revealed a large right parietal tumor in the precentral region with local mass effect. The patient underwent right parietal craniotomy and gross total resection of the tumor. The histopathological report revealed a chondroma. Intradural supratentorial chondromas are extremely rare. As with other slow growing intracranial masses, they often reach a relatively large size before generating symptoms. Maximal surgical resection is the treatment of choice and if this is achieved no adjuvant therapy is necessary.

Chondroma of the falx cerebri: A case report and review of literature

“…The mononucleated cells were enclosed within a chondroid matrix, with no signs of atypia or mitotic activities. Unlike in our case, other studies further performed immunohistochemistry and reported no immunoreactivity for Ki‐67 . Thus, it could be more useful for differentiating chondroma from malignant tumor such as chondrosarcoma or metastasis.…”

“…Intracranial chondroma is a very rare benign cartilaginous tumor with estimated incidence of 0.2% to 0.3% . It mainly arises from the skull base, where it originates from spheno‐petrosal, spheno‐occipital as well as petro‐occipital synchondroses, and seldomly arises from the falx, the dural convexity, or the choroid plexus .…”

“…Intracranial chondroma is a very rare benign cartilaginous tumor with an estimated incidence of 0.2% to 0.3% . The first case was recorded in 1851 by Hirschfield .…”

Intracranial Dural Chondroma: Case Report and Review of Literature

“…They occur intracranially in rare cases with an estimated incidence of 0.2% to 0.5% of all intracranial neoplasms [2]. On the contrary, Connelly et al [3] described less than 30 reported cases in 2018 and found that these lesions can rarely be seen in the parasellar region, at the falx, or arousing from the dura convexity [4].…”

Falcine chondroma: illustrative case

“…1,2 Intracranial chondromas account for 0.2% of all intracranial tumors and were first reported by Hirschfeld in 1851. [3][4][5][6][7][8][9] Rarely, intracranial chondromas can arise from the falx, and we present a middle-aged woman with such a condition. 6,7,10…”