Giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for biomaterial detection applications

Suharyadi, Edi; Pardede, Indra; Ferawati, Artauli Hasibuan

doi:10.1109/piers.2016.7734392

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…The addition of PEG can decrease the agglomeration and reduce the particle size. In addition, ring diffraction patterns for both of them, are closely related to XRD analysis, which corresponding to the crystal plane (220), (311), (400), (440), and (511) [8,10].…”

Section: Resultsmentioning

confidence: 83%

“…The Fe 3 O 4 magnetic nanoparticles were synthesized by chemical co-precipitation method [8,10]. Room temperature VSM measurements have been conducted by using Riken Denshi Co Ltd vibrating sample magnetometer (VSM).…”

Section: Experiments Detailsmentioning

confidence: 99%

“…However, that experiment shows that signal output of GMR sensor was resistance [8]. Even though a unique resistance can be used as sensing element, a Wheatstone bridge setup is always a good recommendation as the starting step in the design of resistive sensors [9].…”

Section: Introductionmentioning

confidence: 99%

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Wheatstone bridge-giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for bio-detection applications

Antarnusa

Swastika

Suharyadi

2018

J. Phys.: Conf. Ser.

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Abstract.A Wheatstone bridge-giant magnetoresistance (GMR) sensor was successfully developed for a potential biomaterial detection. In order to achieve this, a giant magnetoresistive [Co(1.5nm/Cu(1.0nm)] 20 multilayer structures have been fabricated by DC magnetron sputtering method, showing a magnetoresistance (MR) of 2.7%. The X-Ray diffraction (XRD) patterns showed that Co/Cu film multilayer has a high degree of crystallinity with a single peak corresponding to face-centered cubic (111) structure at 2 = 44.1 . Co/Cu multilayers exhibit a soft magnetic behavior with the saturation magnetization (Ms) of 1489 emu/cc and the coercivity (Hc) of 11.2 Oe. The magnetite Fe 3 O 4 nanoparticles used as a bimolecular labels (nanotags) were synthesized via co-precipitation method, exhibiting a soft magnetic behavior with Ms of 77.16 emu/g and Hc of 49 Oe. XRD patterns and transmission electron microscopy (TEM) images showed that Fe 3 O 4 was well crystallized and it grew in their inverse spinel structure with an average size of around 10 nm. The GMR sensor design was used to detect a biomolecules of streptavidin magnetic particles with concentration 10, 20, 30, and 40 l/ml and -amylase enzyme with consentration 10, 20, 30, and 40 l/ml captured using polyethylene glycol (PEG)/ Fe 3 O 4 nanoparticles. Various applied magnetic fields of 0-650 Gauss have been performed using electromagnetic with the various currents of 0-5 A. Here, the final value of the output voltage signals for the streptavidin magnetic particles concentration is 1.2 mV (10 l/ml). The output voltage changes with the increase of concentration. It was reported that the output voltage signal of the Wheatstone bridge exhibits log-linear function in real time measurement of the concentration of streptavidin magnetic particles and -amylase enzyme respectively, making the sensor suitable for use as a biomolecule concentration detector. Thus, the combination of Co/Cu multilayer, Wheatstone bridge, magnetite and PEG polymer has potential application to be used in bio-detection applications where ultra-small bio-labels are needed.

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Section: Resultsmentioning

confidence: 83%

Section: Experiments Detailsmentioning

confidence: 99%

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Wheatstone bridge-giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for bio-detection applications

Antarnusa

Swastika

Suharyadi

2018

J. Phys.: Conf. Ser.

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“…Thereafter, nanoparticles were magnetically separated by attaching an external magnetic field, which was then washed several times with distilled water. The precipitated solution was dried using a furnace at a temperature of 80 °C for 2 hours [9,10]. The Fe3O4 nanoparticles would be characterized using Transmission Electron Microscopy (TEM) and Vibrating Sample Magnetometer (VSM) Riken Denshi Co. Ltd.…”

Section: Methodsmentioning

confidence: 99%

Magnetic Nanoparticle Detection Using Wheatstone Bridge Giant Magnetoresistance (GMR) Sensor with Double CoFeB Spin-Valve Thin Films

Suharyadi

Alfansuri

2021

KEM

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The Wheatstone bridge-giant magnetoresistance (GMR) sensor with single and double spin valve thin film was successfully developed for potential biomolecular detection. The GMR sensor with spin valves structure of [Ta (2nm)/IrMn (10nm)/CoFe (3nm)/Cu (2,2nm)/CoFeB (10nm)/Ta (5nm)] was fabricated using DC Magnetic Sputtering method. The Fe3O4 magnetic nanoparticles were synthesized by the co-precipitation method as a magnetic label. The magnetic properties of the Fe3O4 nanoparticles measured are the saturation magnetization (Ms) of 77.7 emu/g, remanence magnetization (Mr) of 7.7 emu/g, and coercivity (Hc) of 49 Oe. The X-ray diffraction pattern showed the inverse cubic spinel structure with an average crystal size of about 20.1 nm. Fe3O4 magnetic nanoparticles with various concentrations were used to be detected using a GMR sensor. The output voltage of the GMR sensor with the single and double spin-valve increased from 1.7 to 3.9 mV and 2.9 to 5.3 mV with the increase of the Fe3O4 concentration from 0 to 20 mg/mL, respectively.

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Commercial chip-based tunneling magnetoresistance sensor for green-synthesized magnetic nanoparticles assay

Swastika,

Ardiyanti,

Zurnansyah

et al. 2024

Sensors International

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Giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for biomaterial detection applications

Cited by 4 publications

References 8 publications

Wheatstone bridge-giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for bio-detection applications

Wheatstone bridge-giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for bio-detection applications

Magnetic Nanoparticle Detection Using Wheatstone Bridge Giant Magnetoresistance (GMR) Sensor with Double CoFeB Spin-Valve Thin Films

Commercial chip-based tunneling magnetoresistance sensor for green-synthesized magnetic nanoparticles assay

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