Giant Subcutaneous Leiomyosarcoma at Knee Joint:Malignant Tumour at Rare Site

Kumar, Sanjeev; Bhadani, Punam Prasad; Saxena, Renu; Shuchismita,; Kumar, KM Prasanna

doi:10.19056/ijmdsjssmes/2016/v5i2/100622

Cited by 1 publication

(3 citation statements)

References 8 publications

(17 reference statements)

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“…The immunohistochemical analysis observed in this study is in agreement with other studies on leiomyosarcoma (Kumar et al, 2016;Sazaki et al, 2016;Anzai et al, 2017), allowing the diagnostic conclusion.…”

Section: Discussionsupporting

confidence: 92%

“…Most reports about this neoplasm focus on its occurrence in humans (Daudia et al, 2001;Piovanello et al, 2007;Patrono et al, 2014). Giant leiomyosarcoma has been reported in humans in different tissues, such as kidney (Öziş, et al, 2014), uterus (Senol et al, 2016), subcutaneous tissues (Kumar et al, 2016), and rectum (Anzai, 2017). However, no reports of giant leiomyosarcoma in canine species have been reported.…”

Section: Discussionmentioning

confidence: 99%

“…The occurrence of necrotic areas, hemorrhage, pale areas (Morais, Argyle and O´Brien, 2010;Comazzi and MacNeill, 2017), and involvement of the omentum with the tumor mass (Fossum and Caplan, 2015) found here are compatible with cases reported in the literature. Moreover, leiomyosarcoma may assume large dimensions in a short time (Senol et al, 2016;Kumar et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

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Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings

et al. 2017

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Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors.

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Section: Discussionsupporting

confidence: 92%