Gibt es eine Lateralisierung bei der Schmerzverarbeitung von Hitze- und Kälteschmerz?

Processing of sensory, painful and vestibular stimuli in the thalamus

“…The analysis of the first 3 s of heat stimulation, examined Table 3 Local maxima of early (1-3 s) vs. late (4-14 s) thalamic responses to stimulation: cluster sizes, MNI coordinates and cluster level tests using threshold-free cluster enhancement (TFCE) TNA thalamic nuclei atlas, A anterior, CL central-lateral/lateral-posterior/medial-pulvinar, MD medio-dorsal, P pulvinar, VA ventral-anterior, VLD ventral-latero-dorsal, VLV ventral-latero-ventral, OTCA oxford thalamic connectivity atlas, OC occipital cortex, PFC pre-frontal cortex, PPC posterior parietal cortex, PreMC pre-motor cortex, PriMC primary motor cortex, SC sensory cortex, TC temporal cortex a As two tests are performed for each stimulus type and time frame (two stimulation sides) the significance threshold according to Bonferroni is set to α = 0.025 to overcome habituation processes (Treede et al 1995), also did not result in BOLD responses within the thalamus. The same protocol to elicit heat pain has been used in prior experiments of our study group and evoked reliable activations (e.g., of the insula, ACC, and S1) but not within the thalamus (Habig et al 2017;Schirner et al 2014). In a multivariate pattern analysis to decode the perception of laserevoked pain, no significant thalamic activation occurred during laser-evoked pain stimulation or anticipation of pain (Brodersen et al 2012).…”

“…The analysis of the first 3 s of heat stimulation, examined to overcome habituation processes (Treede et al 1995 ), also did not result in BOLD responses within the thalamus. The same protocol to elicit heat pain has been used in prior experiments of our study group and evoked reliable activations (e.g., of the insula, ACC, and S1) but not within the thalamus (Habig et al 2017 ; Schirner et al 2014 ). In a multivariate pattern analysis to decode the perception of laser-evoked pain, no significant thalamic activation occurred during laser-evoked pain stimulation or anticipation of pain (Brodersen et al 2012 ).…”