Ginger: a systematic review of clinical trials and recent advances in encapsulation of its bioactive compounds

Abstract

Recently, studies on natural products have considerably increased due to their exceptional biological activities and health benefits. Subsequently, their pharmacological attributes have played an immense role in detecting natural and...

Acrylamide-Based Saliva-Gels as a Potential Xerostomia Treatment

“…Commercial shortterm treatment methods include consumable salivary liquids/ gels, 14 removable neuro-stimulating devices (e.g., GenNarino), 15,16 pharmaceutics, and natural products. 17 Both the current short-and long-term treatments have their respective drawbacks. Several of these treatments, including pharmaceuticals, are costly and can produce adverse side effects.…”

“…Short-term relief can be provided using wearable reservoirs (e.g., bite guards), , which may contain various solutions, such as mouthwash-containing betaine, or lipid-based lubrications dispensed by topical sialagogue sprayers. Commercial short-term treatment methods include consumable salivary liquids/gels, removable neuro-stimulating devices (e.g., GenNarino), , pharmaceutics, and natural products . Both the current short- and long-term treatments have their respective drawbacks.…”

6-Gingerol-derived semisynthetic analogs mitigate oxidative stress, and reverse acrylamide induced neurotoxicity in zebrafish

“…[1][2][3] Phenolic natural products, especially 6-gingerol, which is one of the major constituents of fresh ginger, have been studied extensively for their broad-spectrum biological properties such as anticancer, anti-diabetic, anti-inflammation and neurotoxicity by modulating signalling pathways/targets, namely HIF-1a, TNF-a, RIP3 and NF-kB, etc. [4][5][6][7] Although several molecular targets are being explored, methodologies that enable the preparation of new chemical entities through a semisynthetic approach are surprisingly lacking. Developing new methodologies not only enables the study of the systematic structure-activity relationship for a therapeutic application but can also help to validate more molecular targets.…”

Ginger Update

“…Ginger powder, extracts, and individual bioactive compounds are also packaged as dietary supplements. Ginger-containing food products are present in many cuisines because of its distinctive sensory qualities, described as pungent, spicy, flowery, lemon-like, warm, camphoraceous, and nutmeg-like, depending on the specific form of ginger and cultivar evaluated 1–7 . Ginger's culinary uses are quite varied.…”

“…Ginger-containing food products are present in many cuisines because of its distinctive sensory qualities, described as pungent, spicy, flowery, lemon-like, warm, camphoraceous, and nutmeg-like, depending on the specific form of ginger and cultivar evaluated. [1][2][3][4][5][6][7] Ginger's culinary uses are quite varied. Laban ma' zanjabeel is a popular yogurt-ginger appetizer in the Middle East and North Africa.…”