Gingerol supplementation does not change glucose tolerance, lipid profile and does not prevent weight gain in C57BL/6 mice fed a high-fat diet

Zordan, Aline Jose Coelho Moreira; Bertoncini-Silva, Caroline; Joaquim, Anderson Gregorio; Rodrigues, Marina; Machado, Cássia Dias; Carlos, Daniela; Foss‐Freitas, Maria Cristina; Suen, Vívian Marques Miguel

doi:10.1016/j.yclnex.2020.05.001

Cited by 4 publications

(3 citation statements)

References 28 publications

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“…The glucose tolerance test followed a previously standardized methodology. 27,28 It was performed after a 10 h fasting period, along with the first blood collection (time 0) by a cut at the caudal end of the animal. Subsequently, a glucose solution of 1 mg g −1 of the animal's weight was injected intraperitoneally.…”

Section: Glucose Tolerance Test (Gtt)mentioning

confidence: 99%

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Beneficial effects of eugenol supplementation on gut microbiota and hepatic steatosis in high-fat-fed mice

et al. 2022

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Section: Glucose Tolerance Test (Gtt)mentioning

confidence: 99%

“…Total cholesterol, triglycerides and HDL were analyzed by enzymatic method using commercial kits from Labtest (Labtest Diagnóstica S.A., Brazil). 27,28…”

Section: Biochemical Analysismentioning

confidence: 99%

Beneficial effects of eugenol supplementation on gut microbiota and hepatic steatosis in high-fat-fed mice

et al. 2022

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“…There are various studies reported about the essential oils related to this genus, such as sabinene from Z. capitatum (Mektrirat et al, 2020;Okonogi and Chaiyana, 2012), zerumbone from Z. zerumbet, Z. ottensii, and Z. roseum (Al-Amin et al, 2019;Chien et al, 2016;Thitinarongwate et al, 2021;, gingerol from Z. officinale (Zordan et al, 2020), and myrcene from Zingiber nimonii (Nair et al, 2019). Furthermore, Chandra et al (2017) has explicitly identified the essential oils of Z. chrysanthum, including geranyl linalool (Table 3).…”

Section: Bioactive Compoundsmentioning

confidence: 99%

A Study of Genus Zingiber: The Role of Condiments in Science

Paramita

Wibowo

Insanu

2021

CRBB

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Background and purpose: Zingiberaceae family has been widely used as an herbal medicine from generation to generation. This review aimed more in-depth into information and correlation about the empirical uses, bioactive compounds, and biological activities, a literature review genus Zingiber was conducted. Methods: Articles about genus Zingiber were collected from databases (e.g., DOAJ (Directory of Open Access Journal), PubMed, ResearchGate, ScienceDirect, and Springer), they were sorted based on inclusions criteria such as; related to bioactive compounds and biological activities of the samples and also articles for the last ten year. Results: The screening results obtained 52 reports to review and grouped according to each plant's bioactive content and pharmacological effect. The extensive constituent in genus Zingiber is essential oil. Therefore, the major activity found in this genus was related to antimicrobial and anti-oxidant. Furthermore, the other activities of plants were related to their factual use during this time. Conclusion: The empirical uses of these rhizomes were in line with the bioactive compounds and biological activities.

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Suplementos dietéticos comerciales para el control de sobrepeso: fuentes naturales de fácil acceso, mecanismos de acción y efectos adversos

Riascos

Trujillo

Mendoza

2022

Rev Esp Nutr Hum Diet

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Introducción: El uso de suplementos dietéticos es una de las estrategias actualmente más implementada por la población para contrarrestar el sobrepeso u obesidad debido a su fácil y rápida adquisición en Internet, pese a que muchos de ellos no cuenten con un respaldo científico que justifiquen su efectividad y seguridad. En esta revisión se describen los mecanismos de acción y efectos adversos de los principales suplementos para el control de sobrepeso de venta online en el mercado colombiano. Material y métodos: En las plataformas de compra online: Amazon, eBay, Walmart, Alibaba, Aliexpress y Mercado libre (Colombia), se identificaron las fuentes naturales de los suplementos dietéticos más destacados (Coffea arábica, Camellia sinensis, Garcinia cambogia, Rubus idaeus, Moringa oleifera, Smallanthus sonchifolius, Cinnamomum verum, Capsicum frutescens L, Cynara scolymus, Zingiber officinale y Hibiscus sabdariffa). Se realizó una revisión siguiendo las recomendaciones propuestas por la declaración PRISMA. Las bases de datos utilizadas para la búsqueda de los artículos entre 2010 y 2020 fueron ScienceDirect, PubMed, SCOPUS, SciELO, Web of Science y el buscador Google académico. Un total de 189 referencias fueron contempladas. Resultados: Los principios bioactivos (aislados o en extractos) identificados en las fuentes naturales fueron: polifenoles, teaflavinas, (-)-epigalocatequina-3-O-galato (EGCG), (-)-3-O-(3-O-metil) galato de epigalocatequina (EGCG3), ácido clorogénico, cinamaldehído y ácido hidroxicítrico (HCA), que han demostrado en cultivos celulares y en animales modelo, su capacidad para regular el metabolismo energético, disminuir la lipogénesis, aumentar la oxidación de ácidos grasos e inhibir su síntesis, regular la ingesta de alimentos, entre otras. La hepatotoxicidad y los problemas gastrointestinales con sintomatología leve o moderada, son los efectos adversos más comunes asociados al consumo de este tipo de fuentes. Conclusiones: El efecto en la pérdida de peso de las fuentes naturales abordadas en esta revisión, está científicamente respaldada con ensayos in vitro e in vivo con animales, pero debido al escaso soporte científico evidenciado a partir de ensayos clínicos controlados aleatorizados, es necesario realizar más estudios para establecer la objetividad de lo observado y evaluar la seguridad del uso de los suplementos dietéticos derivados para el control de sobrepeso.

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Gingerol supplementation does not change glucose tolerance, lipid profile and does not prevent weight gain in C57BL/6 mice fed a high-fat diet

Cited by 4 publications

References 28 publications

Beneficial effects of eugenol supplementation on gut microbiota and hepatic steatosis in high-fat-fed mice

Beneficial effects of eugenol supplementation on gut microbiota and hepatic steatosis in high-fat-fed mice

A Study of Genus Zingiber: The Role of Condiments in Science

Suplementos dietéticos comerciales para el control de sobrepeso: fuentes naturales de fácil acceso, mecanismos de acción y efectos adversos

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