Gleason underestimation is predicted by prostate biopsy core length

Reis, Leonardo Oliveira; Sanches, Brunno Cezar Framil; Mendonça, Gustavo; Silva, Daniel M.; Aguiar, Tiago; Menezes, Ocivaldo P.; Billis, Athanase

doi:10.1007/s00345-014-1371-9

Cited by 18 publications

(8 citation statements)

References 20 publications

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“…Prostate core lengths has been correlated with GS underestimation risk. 39,40 Thus a better matching was obtained in increasing the number of core 41,42 and the prostate sampling volume. 43,44 Rapiti et al 24 found that the proportion of exact matching improved significantly when patients had ⩾ 10 cores compared with those who had ⩽ 9.…”

Section: Discussionmentioning

confidence: 93%

Preoperative low serum testosterone is associated with high-grade prostate cancer and an increased Gleason score upgrading

Pichon

Neuzillet

Botto

et al. 2015

Prostate Cancer Prostatic Dis

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Section: Discussionmentioning

confidence: 93%

Preoperative low serum testosterone is associated with high-grade prostate cancer and an increased Gleason score upgrading

Pichon

Neuzillet

Botto

et al. 2015

Prostate Cancer Prostatic Dis

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“…All of cores biopsy were obtained in the same manner under the coordination of three experienced urologists of our Department. Reis et al (26) evaluated the clinical impact of the core length on the PCa diagnosis and pathologic upgrade in the setting of an experienced performer (>250 PBx/year) opposing to in-training urology residents. However, several limitations need to be acknowledged.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Core Length on Prostate Cancer Diagnosis during a Standard 14-Core Prostate Biopsy Scheme

Dell’Atti¹,

Ippolito²

2016

Urologia

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“…), operator skill (e.g., learning curve etc. ), location and number of cores, core length ( 25 , 26 ). In our study, all of these parameters were similar in each group, except the core length which was not evaluated.…”

Section: Discussionmentioning

confidence: 99%

Local anesthesia type affects cancer detection rate in transrectal ultrasound guided prostate biopsy

et al. 2015

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Purpose:Studies about the anesthesia techniques during transrectal ultrasound guided prostate biopsy (TRUS-Bx) are usually focused on pain relief. Although patients' tolerance is an important issue in TRUS-Bx, cancer detection rate (CDR) must not be ignored. In this study, we compared the impact of intrarectal lidocaine gel anesthesia (IRLA) and periprostatic nerve blockade (PNB) techniques on CDR.Materials and Methods:A total of 422 patients underwent 10 core-TRUS-Bx because of elevated serum prostate specific antigen (PSA) level (>2.5ng/mL) and/or suspicious digital rectal examination findings. Patients were divided into two groups according to the applied anesthesia technique: IRLA group and PNB group. Age, serum PSA level, prostate volume, visual analogue scale (VAS) score and CDR were recorded and compared statistically with chi square and unpaired t-tests.Results:Of the patients 126/422 (29.9%) underwent TRUS-Bx by using IRLA whereas 296/422 (70.1 %) by PNB technique. The mean, age, serum PSA level and prostate volume were similar between the two groups. CDR was 19.8% and 25.4% in IRLA and PNB groups, respectively (p=0.001). The mean VAS score of the PNB group (1.84±0.89) was significantly lower than that for IRLA group (3.62±1.06) (p=0.001). Conclusions: Our results revealed that PNB is superior to IRLA in terms of CDR. Further studies are required to confirm our findings.

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Gleason underestimation is predicted by prostate biopsy core length

Abstract: While core length on trans-rectal biopsy independently affects Gleason upgrading on RP specimens, performer experience has minor impact on Gleason discordance or biopsy positivity due to a sharp learning curve.

Cited by 18 publications

References 20 publications

Preoperative low serum testosterone is associated with high-grade prostate cancer and an increased Gleason score upgrading

Preoperative low serum testosterone is associated with high-grade prostate cancer and an increased Gleason score upgrading

The Impact of Core Length on Prostate Cancer Diagnosis during a Standard 14-Core Prostate Biopsy Scheme

Local anesthesia type affects cancer detection rate in transrectal ultrasound guided prostate biopsy

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