Global Asthma Network Phase I, India: Results for allergic rhinitis and eczema in 127,309 children and adults

Barne, Monica; Singh, Sheetu; Mangal, Daya Krishan; Singh, Meenu; Awasthi, Sanjay; Mahesh, Padkuduru A.; Kabra, Sushil Kumar; Mohammed, Sabir; Sukumaran, T. U.; Ghoshal, Aloke Gopal; Sinha, Sanjeev; Kochar, Sanjay Kumar; Singh, Nishtha; Singh, Udaiveer; Patel, Kamalesh Kumar; Sharma, Arvind Kumar; Girase, Bhushan; Madas, Sapna; Chauhan, Anil K.; Sit, Niranjan; Siddaiah, Jayaraj Biligere; Singh, Virendra; Salvi, Sundeep

doi:10.1016/j.jacig.2022.01.004

Cited by 12 publications

(40 citation statements)

References 36 publications

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“…The prevalence of asthma in USA was 6.4%–10.8% & 19.1% and Europe 10.1% & 15.3% among 6–7 and 13–14‐year‐olds, respectively 24 . Figure 1 summarizes AR prevalence among children aged 6–7 years and 13–14 years in different Indian locations from the ISAAC and the GAN phase I, India study 14,22,25 …”

Section: Methodsmentioning

confidence: 99%

“…Adults : The INSEARCH study (2012) involving 169,575 subjects reported a prevalence of 3.45% for AR in Indian adults 26,27 . The GAN adult study observed an increase in prevalence at 9.8% (2019) 22 . Allergic rhinitis is the most frequent co‐morbidity in asthma, and a recent survey of asthmatics from urban areas showed a prevalence of 65.4% 28,29 .…”

Section: Methodsmentioning

confidence: 99%

“…Sedentariness: Sedentary lifestyle is associated with central obesity, a risk factor for allergic diseases 94 . In India, sedentary behaviour is associated with increased allergic disease 22 . Sedentary behaviour and lower aerobic fitness are associated with increased airway inflammation and lower regulatory T cell responses 95 …”

Section: Key Determinants Of Allergic Diseases In Indiamentioning

confidence: 99%

“…75 Air pollution: Indoor air pollution from cooking fuels, incense, mould and cleaning materials is associated with increased asthma. 22,63,68 Both indoor pollution and outdoor pollution from traffic and industry are associated with asthma, AR and AD. 22,61 Climate change: This is likely to have a major impact on asthma and AR, through increased pollen count, dispersal and allergenicity, but more studies are needed.…”

Section: Specific Influences On Allergic Diseasesmentioning

confidence: 99%

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Allergic diseases in India – Prevalence, risk factors and current challenges

Anand

Moitra

Mabalirajan

et al. 2022

Clin Experimental Allergy

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Epidemiological studies have shown a rise in the prevalence of allergic diseases in India during the last two decades. However, recent evidence from the Global Asthma Network study has observed a decrease in allergic rhinitis, asthma and atopic dermatitis in children. Still, with a population over 1.3 billion, there is a huge burden of allergic rhinitis, asthma and atopic dermatitis, and this is compounded by an unmet demand for trained allergy specialists and poor health service framework. There is wide variation in the prevalence of allergic diseases between different geographical locations in India, and the reasons are unclear at present. This may at least in part be attributable to considerable heterogeneity in aero-biology, weather, air pollution levels, cultural and religious factors, diet, socioeconomic strata and literacy. At present, factors enhancing risks and those protecting from development of atopy and allergic diseases have not been well delineated, although there is some evidence for the influence of genetic factors alongside cultural and environmental variables such as diet, exposure to tobacco smoke and air pollution and residence in urban areas. This narrative review provides an overview of data from India regarding epidemiology, risk factors and genetics and highlights gaps in evidence as well as areas for future research.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Key Determinants Of Allergic Diseases In Indiamentioning

confidence: 99%

Section: Specific Influences On Allergic Diseasesmentioning

confidence: 99%

See 2 more Smart Citations

Allergic diseases in India – Prevalence, risk factors and current challenges

Anand

Moitra

Mabalirajan

et al. 2022

Clin Experimental Allergy

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“…Identifying the etiological factors formed the core basis of ISAAC phase II (1998) while the ISAAC phase III study (2001)(2002)(2003) imitated phase 1 for evaluating 1.9 million children from 98 countries and found a wide heterogeneity in the prevalence of AR and eczema globally. In India, the ISAAC phase III showed the prevalence of AR and ARC as 11.3% (7.3%, 26.7%) and 3.9% (1.8%, 8.6%), respectively, in the 6-7-year-olds and 24.4% (4.1%, 45.7%) and 10.9% (0.9%, 23.6%) in the 13-14-year-olds, respectively 3 .The Global Asthma Network (The GAN) continued the work that ISAAC (concluded 2012) had initiated and extended the survey to include parents of children participating in the study to bridge the data gap about the prevalence of asthma, AR, and eczema in adults especially in the low-and middle-income countries 1 .…”

Section: Introductionmentioning

confidence: 99%

Quality of Life Assessment in Children and Their Caregivers Suffering From Allergic Rhinitis and/or Asthma

Wadhawan¹,

Gupta²,

Prakriti³

et al. 2023

Preprint

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Introduction: Asthma and Allergic Rhinitis (AR) are among the most prevalent diseases worldwide and they frequently persist throughout life. These have significant effect on physical, financial and mental wellbeing of patients and caregivers. There have been few attempts previously, assessing quality of life in affected families suffering from these diseases. However, data from developing countries are scarce. Quality of life (QOL) assessment in children and caregivers of patients suffering can help in symptomatic management and provide inputs for better utilization of resources to achieve optimal treatment. Methods: Patient and caregiver QOLs were ascertained using mPAQLQ and PACQLQ respectively in the study and correlated with disease severity and chronicity using parametric and non-parametric statistical tools. Results: There were 246 pairs of children diagnosed with Asthma and/or AR and their caregivers attending the Pediatric Allergy and Asthma clinic. Symptom score, emotional domain and activity limitation in children did not validate a statistically significant difference in QOL in various grades of AR/Asthma (p=0.632)(p=0.772), (p=0.496) (p=0.918) and (p=0.384), (p=0.561) respectively. Additionally there was no significant correlation between the severity of asthma and caregiver emotional disturbance (p=0.594) or caregiver activity limitation (p=0.446). Conclusions: Quality of life in children and caregivers where children are suffering from either AR or Asthma, or both has not shown any significant difference as per the disease severity or chronicity in various domains. There was no significant difference in quality of life noted as per change in age group, gender of patients or education status of caregivers.

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