Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures

Wang, Jianwen; Khoury, Dirar S.; Thohan, Vinay; Torre‐Amione, Guillermo; Nagueh, Sherif F.

doi:10.1161/circulationaha.106.662882

Cited by 355 publications

(294 citation statements)

References 28 publications

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“…Global longitudinal strain and strain rate curves were obtained in 156 patients, including all six LV myocardial segments from 4-chamber, 2-chamber, and long-axis apical views [21][22][23]. The average values of peak systolic longitudinal strain and peak systolic strain rate from the 3-apical views were calculated as global longitudinal strain (LS SYS ) and global strain rate (SR SYS ), respectively.…”

Section: Methodsmentioning

confidence: 99%

Nonalcoholic fatty liver disease is independently associated with early left ventricular diastolic dysfunction in patients with type 2 diabetes

Mantovani

Pernigo

Bergamini

et al. 2015

Digestive and Liver Disease

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Section: Methodsmentioning

confidence: 99%

Nonalcoholic fatty liver disease is independently associated with early left ventricular diastolic dysfunction in patients with type 2 diabetes

Mantovani

Pernigo

Bergamini

et al. 2015

Digestive and Liver Disease

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“…There is evidence in an animal model that segmental early diastolic SR correlates with the degree of interstitial fibrosis 139 . Moreover, reduced early diastolic SR has been observed in patients with hypertension and DD 140 and a significant relationship was observed between segmental 141 and global 142 early diastolic SR and τ.…”

Section: Diastolic Strain/strain Ratementioning

confidence: 96%

“…In a recent study that combined GSR IVR and transmitral flow velocities, the mitral E velocity/GSR IVR ratio predicted LV filling pressure in patients in whom the E/E' ratio was inconclusive and was more accurate than E/E' in patients with normal LVEF and those with regional dysfunction 142 . Although promising, accurate measurements of GSR IVR are dependent on high‐quality signals with good myocardial visualisation.…”

Section: Diastolic Strain/strain Ratementioning

confidence: 99%

Echocardiographic evaluation of diastolic heart failure

Thomas

2010

Australas J Ultrason Med

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“…15,16 Strain rate during the isovolumetric relaxation time (IVRsr) or early diastolic strain rate (e´sr), derived from global longitudinal speckletracking strain, were recently proposed to estimate LV filling pressures, although both parameters are still experimental. 17 …”

Section: Diastolic Functionmentioning

confidence: 99%

Novel Imaging Techniques for Heart Failure

Melero-Ferrer

López‐Vilella

Morillas-Climent

et al. 2016

Cardiac Failure Review

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Heart failure (HF) is an epidemic with an increasing prevalence and an absolute mortality rate of approximately 50 % within 5 years of diagnosis. Imaging plays a main role in HF diagnosis, assessment of aetiology and treatment guidance. This article reviews current HF applications for all the available non-invasive imaging modalities: echocardiography, cardiovascular magnetic resonance (CMR), nuclear imaging-positron emission tomography (PET) and single-photon emission computed tomography (SPECT) and computed tomography (CT). Echocardiography, with its recent developments, such as 3D echo, is the main imaging test used in the evaluation of HF patients, given its availability and reliability in assessing cardiac structure and function. CMR allows the characterisation of myocardial tissue, in addition to providing information on the structure and cardiac function, so it is a great help in the determination of HF aetiology and may predict patient outcomes. Nuclear imaging can detect ischaemia and viability and can obtain additional prognostic data. Cardiac CT is EchocardiographyAlthough echocardiography is a relatively 'ancient' technique, its versatility makes it unique in the provision of volumes, function, haemodynamics or valvular regurgitation. In addition, because of its availability, safety and low cost, echocardiography is the first and most widely used test for the diagnosis, selection of appropriate treatment and prognosis of HF.1 Echocardiography is also the most used imaging method in the reassessment of HF patients. It remains unclear when to repeat echocardiographic exams, but it is deemed appropriate at least in patients with worsening symptoms. Systolic FunctionGlobal left ventricular (LV) function is of paramount importance regarding therapeutic decisions. Visual estimation of ejection fraction (EF), the Teichholz and Simpson methods, have been widely validated. 2,3However, in 2D imaging, because of its operator-dependent nature, repeated testing has a high probability of producing variable volume and EF results.The apparition of 3D fully sampled matrix transthoracic echocardiography has enabled easier acquisition of images, 4 simplifying its routinary application. There have been many studies comparing 2D and 3D echocardiography (2DE and 3DE) and a 'reference' standard (generally CMR). A recent meta-analysis of all 3DE studies evaluating LV volumes and EF demonstrated that 3DE generally underestimated volumes, but not as significantly as 2DE. There was also less variability than 2D compared with CMR.5 Nonetheless, 3DE echocardiography may be challenging and not practical in patients with low image quality (e.g. critical patients), in whom 2DE measures are more realiable. 3DE is also a less standardised techique than 2DE, and because of this reason most laboratories use the more universally applicable 2DE measurements in clinical practice. Only recently, large analyses of LV parameters using 3DE in large cohorts of healthy individuals have been published to establish race, age and gender-specific ...

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Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures

Cited by 355 publications

References 28 publications

Nonalcoholic fatty liver disease is independently associated with early left ventricular diastolic dysfunction in patients with type 2 diabetes

Nonalcoholic fatty liver disease is independently associated with early left ventricular diastolic dysfunction in patients with type 2 diabetes

Echocardiographic evaluation of diastolic heart failure

Novel Imaging Techniques for Heart Failure

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