Global Longitudinal Strain to Predict Mortality in Patients With Acute Heart Failure

Park, Jin Joo; Park, Jun Bean; Park, Jae‐Hyeong; Cho, Goo Yeong

doi:10.1016/j.jacc.2018.02.064

Cited by 324 publications

(262 citation statements)

References 26 publications

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“…In addition, peri‐infarct strain is the only independent predictor of malignant cardiac arrhythmias, and GLS could identify patients at risk of ventricular arrhythmias despite LVEF is >35% . Even in the setting of acute HF, for a given LVEF, there is a wide distribution of LV dyssynchrony, and LV dyssynchrony appears to have a greater prognostic role than LVEF …”

Section: Left Ventricular Ejection Fraction Based Classification: Oppmentioning

confidence: 99%

Heart failure with mid‐range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

et al. 2020

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Currently, the assessment of left ventricular ejection fraction (LVEF) is the cornerstone of the classification of patients with heart failure (HF). The mid-range LVEF (HFmrEF) category was identified in an attempt to uncover specific characteristics of these patients. So far, the analysis of trials, registries, and observational studies have demonstrated that patients with midrange LVEF belong to a patient cohort with generally intermediate clinical profile as compared with other groups but with a remarkable variety of intrinsic phenotypes. This is due to the limitations of LVEF as the sole criterion to categorize patients with HF and characterize their prognosis, above all when it is >40%. To better define the HFmrEF phenotype, it is reasonable to consider other parameters, such as LVEF changes over time, HF aetiology, co-morbidities, and other imaging parameters. A multiparametric evaluation may contextualize a patient with HFmrEF in a more defined phenotype with a specific prognosis.

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Section: Left Ventricular Ejection Fraction Based Classification: Oppmentioning

confidence: 99%

Heart failure with mid‐range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

et al. 2020

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“…6 Also, it is now generally accepted that LVEF is an insufficient marker of prognosis in HF. 26 As shown in Figure 7, biventricular and left atrial deformation is impaired in a patient with HFmrEF, suggesting that LVEF may be a criterion of definition but not enough to estimate global cardiac function.…”

Section: He Art Failure With Mid -R Ang E LV E Fmentioning

confidence: 99%

“…The objective of this review is not to address the controversy, and the authors of this review would like to point out that in a chronically failing heart, multiple chambers are involved in addition to the LV . Also, it is now generally accepted that LVEF is an insufficient marker of prognosis in HF …”

Section: Heart Failure With Mid‐range Lvefmentioning

confidence: 99%

Biatrial and right ventricular deformation imaging: Implications of the recent EACVI consensus document in the clinics and beyond

et al. 2019

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In this review, right ventricular (RV), right atrial (RA), and left atrial (LA) strain in some selected clinical situations has been discussed in light of the current literature. To exemplify the significance of the use of multichamber strain, we have provided some illustrations of common cardiac problems. The recently published European Association of Cardiovascular Imaging (EACVI) consensus document for standardization of RV, RA, and LA strain, using the currently available software, has fulfilled the aspirations of investigators world over who have been studying atrial strain using a bailed‐out algorithm designed principally to quantify left ventricular deformation. The purpose of this review was to reiterate the value of the application of RV and biatrial strain imaging in research and day‐to‐day clinical practice, using the 2‐dimensional speckle tracking echocardiography (2D‐STE). Also, we present a short report on how RA strain may remain coupled to pulmonary hemodynamics. Besides, we have highlighted the technical challenges of atrial strain quantification. We have not used the nomenclature of chamber deformation proposed by the EACVI document as the publications cited in this review have used different sets of nomenclature.

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“…Measurement of LVEF is imprecise as it can fluctuate significantly depending on loading conditions, imaging modality used, and inter-observer variability [19]. LVEF is also less sensitive in HFpEF than other imaging calculations such as global longitudinal strain at detecting systolic dysfunction [20] and predicting mortality [21]. Serum biomarkers are being investigated to further our understanding of the pathophysiology of HFpEF (see Figure 1).…”

Section: Introductionmentioning

confidence: 99%

Biomarkers in Heart Failure With Preserved Ejection Fraction: An Update on Progress and Future Challenges

Carnes

Gordon

2020

Heart, Lung and Circulation

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Global Longitudinal Strain to Predict Mortality in Patients With Acute Heart Failure

Abstract: In patients with acute HF, GLS has greater prognostic value than LVEF. Therefore, the authors suggest that GLS should be considered as the standard measurement in all patients with HF. This new concept needs validation in further studies.

Cited by 324 publications

References 26 publications

Heart failure with mid‐range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

Heart failure with mid‐range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

Biatrial and right ventricular deformation imaging: Implications of the recent EACVI consensus document in the clinics and beyond

Biomarkers in Heart Failure With Preserved Ejection Fraction: An Update on Progress and Future Challenges

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