Global Research Trends in Single-Cell Sequencing in Degenerative Disease Research: A Bibliometric and Visualization Study

Abstract

The role of single-cell sequencing in degenerative diseases has attracted significant attention in current research. This study aims to investigate the global status and emerging trends in this field. The literature on single-cell sequencing in degenerative diseases was retrieved from January 1, 1991 to September 1, 2023, utilizing the Web of Science Citation Index Expanded. The source data was analyzed using bibliometric methods. To visualize the research findings, VOS viewer version 1.6.19 software was employed for co-authorship analysis, co-occurrence analysis, bibliographic coupling, and co-citation analysis. The study also evaluated the overall trend of single-cell sequencing in degenerative disease research in recent years. A total of 1430 articles were retrieved, reflecting a continuous increase in research and publications on single-cell sequencing in degenerative diseases worldwide. The United States has played a prominent role in this field, contributing the highest number of publications and citations, as well as having the highest h-index. Springer Nature and Frontiers Media Sa emerged as the leading publishers.