Global Risk Profile Verification in Patients with Venous Thromboembolism (GRIP VTE) in 5 Gulf Countries

Sayegh, Faisal Al; Almahmeed, Wael; Humood, Salah Al; Marashi, Mahmoud; Bahr, Ahmed; Mahdi, Hasan Al; Bakir, Sherif; Farhan, Maha Al

doi:10.1177/1076029608315168

Cited by 13 publications

(14 citation statements)

References 30 publications

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“…The only study that assessed VTE risk and adequacy of prophylaxis in the Arabian Gulf states (Kuwait, Saudi Arabia, and the UAE) emerged from the global ENDORSE study [23]. However, this study was mainly based on selected surgical and medical patients rather than pregnant women.…”

Section: Discussionmentioning

confidence: 99%

Venous Thromboembolism Risk and Adequacy of Prophylaxis in High Risk Pregnancy in the Arabian Gulf

Alsayegh

Al-Jassar

Wani

et al. 2016

CVP

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Objectives: To estimate the prevalence of venous thromboembolism (VTE) risk factors in pregnancy and the proportion of pregnancies at risk of VTE that received the recommended prophylaxis according to the American College of Chest Physicians (ACCP) 2012 published guidelines in antenatal clinics in the Arabian Gulf.Methods: The evaluation of venous thromboembolism (EVE)-Risk project was a non-interventional, cross-sectional, multi-centre, multi-national study of all eligible pregnant women (≥17 years) screened during antenatal clinics from 7 centres in the Arabian Gulf countries (United Arab Emirates, Kuwait, Bahrain, Qatar and Oman). Pregnant women were recruited during a 3-month period between September and December 2012.Results: Of 4,131 screened pregnant women, 32% (n=1,337) had ≥1 risk factors for VTE. Common VTE risk factors included obesity (76%), multiparity (33%), recurrent miscarriages (9.1%), varicose veins (6.9%), thrombophilia (2.6%), immobilization (2.0%), sickle cell disease (2.8%) and previous VTE (1.6%). Only 8.3% (n=111) of the high risk patients were on the recommended VTE prophylaxis. Enoxaparin was used in 80% (n=89) of the cases followed by tinzaparin (4%; n=4). Antiplatelet agents were prescribed in 11% (n=149) of pregnant women. Of those on anticoagulants (n=111), 59% (n=66) were also co-prescribed antiplatelet agents. Side effects (mainly local bruising at the injection site) were reported in 12% (n=13) of the cases.Conclusion: A large proportion of pregnant women in the Arabian Gulf countries have ≥1 VTE risk factor with even a smaller fraction on prophylaxis. VTE risk assessment must be adopted to identify those at risk who would need VTE prophylaxis.

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Section: Discussionmentioning

confidence: 99%

Venous Thromboembolism Risk and Adequacy of Prophylaxis in High Risk Pregnancy in the Arabian Gulf

Alsayegh

Al-Jassar

Wani

et al. 2016

CVP

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“…Numerous studies have been performed to assess the independent risk factors for VTE. Different studies showed different independent factors: acute infection, age, cancer, previous VTE [12], immobilization, advanced age, previous VTE, trauma [13], hospital or nursing home confinement, surgery, trauma, cancer with/without chemotherapy, neurological diseases with paresis, central venous catheter or pacemaker, varicose veins, and superficial vein thrombosis [14]. In our study, the independent risk factors were the following: previous VTE, obesity, COPD, heart failure, varicose veins, and cancer.…”

Section: Discussionmentioning

confidence: 99%

Risk factors in venous thromboembolism in hospitalized patients

Andercou¹

2014

Open Medicine

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AbstractVenous thromboembolism (VTE) causes considerable morbidity and mortality. About half of all VTE cases in adults are related to recent hospitalization, in spite of the clinical guidelines regarding prophylaxis. We aimed to assess the frequency and the independent risk factors in VTE in hospitalized patients, and to compare the risk factors in medical versus surgical cases. A case-control study consisting of 732 patients (382 with VTE and 350 controls) was designed. At least one risk factor was found in 90.31% of VTE cases; more than half of the patients presented multiple risk factors, associated with a double risk comparatively to the intervention of only one factor. A similar distribution of the risk factors was found in both medical and surgical patients, except for congestive cardiac failure (predominant in medical cases) and respectively, varicose veins, previous episode of VTE and cancer (predominant in surgical VTE patients). The independent risk factors in VTE were the following: previous episode of VTE, obesity, chronic obstructive pulmonary disease, congestive cardiac failure, varicose veins and cancer. The study shows the importance of the risk factors in VTE and the need to detect hospitalized patients at risk in both medical and surgical cases.

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“…There is only one such study [15], which explored VTE risk factors, its rate in surgical and medical wards and the appropriateness of using pharmacologic anticoagulation. This study showed a significant VTE rate in both surgical and medical patients.…”

Section: Introductionmentioning

confidence: 99%

“…This study showed a significant VTE rate in both surgical and medical patients. In addition, there was inappropriate utilization of pharmacologic anticoagulants in patients with established VTE [15]. …”

Section: Introductionmentioning

confidence: 99%

Assessment of Venous Thromboembolism Risk and Adequacy of Prophylaxis in Selected Acute Care Medical Centres in Arabian Gulf States: Results from the ENDORSE Study

Alsayegh

Kamaliddin²,

Sheshah³

et al. 2012

Med Princ Pract

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Objectives: To assess the prevalence of venous thromboembolism (VTE) risk in acutely ill surgical and medical patients in selected acute care centres in the Arabian Gulf States, and to determine the proportion of at-risk patients who received effective prophylaxis in accordance with 2004 American College of Chest Physicians (ACCP) guidelines. Materials and Methods: Eight hospitals from 3 countries (Kuwait, Kingdom of Saudi Arabia, and United Arab Emirates) contributed to the global ENDORSE (Epidemiological International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting) study. Medical records were reviewed for all the in-patients aged ≥40 years admitted to medical wards, and in patients aged ≥18 admitted to surgical wards. The VTE risk and recommended prophylaxis were assessed according to the 2004 ACCP guidelines. Results: Of 1,291 evaluable patients, 801 were considered at risk of VTE; 391 (48.8%) surgical patients and 410 (51.2%) medical patients. Of the 801 patients, 322 (40.2%) received ACCP-recommended VTE prophylaxis; 159 (40.7%) of surgical patients and 163 (39.8%) of medical patients. Conclusions: The data showed that VTE prophylaxis was underutilized in high-risk hospitalized patients. We recommend that active measures should be implemented in acute care centres in these Arabian Gulf countries to ensure identification of patients at risk of VTE and institute the appropriate prophylaxis.

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Global Risk Profile Verification in Patients with Venous Thromboembolism (GRIP VTE) in 5 Gulf Countries

Abstract: VTE remains a common problem in medical and surgical patients in the Arabian Gulf states. Recognition of the common risk factors is of extreme importance to implement the appropriate prophylactic strategy according to the published guidelines.

Cited by 13 publications

References 30 publications

Venous Thromboembolism Risk and Adequacy of Prophylaxis in High Risk Pregnancy in the Arabian Gulf

Venous Thromboembolism Risk and Adequacy of Prophylaxis in High Risk Pregnancy in the Arabian Gulf

Risk factors in venous thromboembolism in hospitalized patients

Assessment of Venous Thromboembolism Risk and Adequacy of Prophylaxis in Selected Acute Care Medical Centres in Arabian Gulf States: Results from the ENDORSE Study

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