Glutaraldehyde allergy in endoscopy units

Calder, Ian; Wright, Logan; Grimstone, D.

doi:10.1016/0140-6736(92)90124-l

Cited by 30 publications

(13 citation statements)

References 2 publications

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“…[18][19][20] However, glutaraldehyde shows a high toxicity and its vapour irritates eyes, nose and throat. 21,22) Formaldehyde also stimulates mucosa and furthermore it is a carcinogen. [23][24][25] The toxicity of cresol is lower and it is used as a disinfectant, but spreading this compound is also harmful.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial Effect of trans-Cinnamaldehyde, (-)-Perillaldehyde, (-)-Citronellal, Citral, Eugenol and Carvacrol on Airborne Microbes Using an Airwasher

Sato

Krist

Buchbauer

2006

Biological & Pharmaceutical Bulletin

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Citral, trans-cinnamaldehyde, (؊)-perillaldehyde, (؊)-citronellal, eugenol and carvacrol were tested for their influence on microbial count in air by vaporizing with an air washer. The highest antibacterial activity was observed when (؊)-perillaldehyde was sprayed. The average reduce of germ count was 53%. On the other hand, the antimicrobial activity of eugenol was the lowest of these six compounds. The average reduction of germ count was 13%. When water without volatile compounds was sprayed, the colony forming units increased. These results suggest the utility of selected aroma-compounds for the control of bacteria in the room.

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Section: Resultsmentioning

confidence: 99%

Antimicrobial Effect of trans-Cinnamaldehyde, (-)-Perillaldehyde, (-)-Citronellal, Citral, Eugenol and Carvacrol on Airborne Microbes Using an Airwasher

Sato

Krist

Buchbauer

2006

Biological & Pharmaceutical Bulletin

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“…Glutaraldehyde exposure is also associated with symptoms such as irritation of the eyes, nose, and throat and headache [Axon et al, 1981;Jachuck et al, 1984;Corrado et al, 1986;Norback, 1988;Bullard, 1991;Macnab, 1991;Adam and Leicester, 1992;Calder et al, 1992;Mwaniki and Guthua, 1992;Waldron, 1992;Leinster et al, 1993;Ellett et al, 1995;Gannon et al, 1995;Pisaniello et al, 1997].…”

Section: Introductionmentioning

confidence: 98%

Symptoms and lung function in health care personnel exposed to glutaraldehyde

Waters

Beach

Abramson

2003

American J Industrial Med

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“…Exposure to glutaraldehyde has been shown to reduce FVC and FEV 1 among current and ex-employees 12,13) . Allergic contact dermatitis and asthma have been reported among health care professionals from occasional or incidental occupational exposure to glutaraldehyde 11,[14][15][16] . As most of the adverse health effects from exposure to glutaraldehyde are related to its irritation and sensitization effects, its recommended that occupational exposure standards are ceiling values.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Work Practices on Personal Exposure to Glutaraldehyde among Health Care Workers

Nayebzadeh¹

2007

Ind Health

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Glutaraldehyde is a potential sensitizer and has been implicated in the literature as a cause of respiratory irritation and asthma among health care workers. In order to evaluate the effect of work practices and general ventilation system on employees' peak exposure to glutaraldehyde, 42 breathing zone personal air samples were taken in five hospitals. In addition, work practices were observed and recorded during the course of sampling and were classified into three categories. Presence of local or general ventilation system, air change per hour, and quantity of glutaraldehyde used were also recorded. Geometric mean concentration of all samples was 0.025 ppm (GSD=3.05). Statistical analysis indicated that work practice was the most important factor affecting the level of exposure to glutaraldehyde. In locations where "poor" or "unsafe" work practices were employed, the geometric mean concentrations were much higher (GM=0.05, GSD=2.11 and GM 0.08, GSD=1.52, respectively). The result has indicated higher prevalence of headache and itchy eyes among employees who worked where unsafe work practices were observed. Employing proper work practices can significantly reduce exposure to glutaraldehyde among health care workers. It has been recently proposed that the current occupational exposure limit of 0.2 ppm shall be reduced to either 0.1 or 0.05 ppm in the province of Québec (Canada). In this case, it is likely that concentration levels higher than these levels be experienced in some workplaces. Therefore, it is imperative that employers initiate necessary corrective action immediately.

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Glutaraldehyde allergy in endoscopy units

Cited by 30 publications

References 2 publications

Antimicrobial Effect of trans-Cinnamaldehyde, (-)-Perillaldehyde, (-)-Citronellal, Citral, Eugenol and Carvacrol on Airborne Microbes Using an Airwasher

Antimicrobial Effect of trans-Cinnamaldehyde, (-)-Perillaldehyde, (-)-Citronellal, Citral, Eugenol and Carvacrol on Airborne Microbes Using an Airwasher

Symptoms and lung function in health care personnel exposed to glutaraldehyde

The Effect of Work Practices on Personal Exposure to Glutaraldehyde among Health Care Workers

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