Glutaraldehyde Exposures and Symptoms among Endoscopy Nurses in South Australia

Pisaniello, Dino; Gun, Richard Townsend; Tkaczuk, Michael N.; Nitshcke, Monika; Crea, Joseph

doi:10.1080/1047322x.1997.10389484

Cited by 32 publications

(33 citation statements)

References 13 publications

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“…Gannon et al 9) reported five cases of occupational asthma due to GA in endoscopy departments, in which median short-term levels were 0.04 ppm during decantation in endoscopy suites. Not only Pisaniello et al 99) but also Vyas et al 100) reported that nurses exhibited significantly higher prevalences of various symptoms with levels of exposure below 0.05 ppm GA. This level is lower than the recommended ones noted above.…”

Section: Assessment Of Exposurementioning

confidence: 99%

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Effects of Glutaraldehyde Exposure on Human Health

Takigawa

Endo

2006

Journal of Occupational Health

248

147

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Section: Assessment Of Exposurementioning

confidence: 99%

“…A cross-sectional study of 135 nurses (including 105 nurses working in operating rooms) using GA solutions for cold instrument sterilization was conducted in 26 hospitals in South Australia 99) . Three hospitals used 2% GA solution, and the remaining 23 hospitals used 1% GA solution.…”

Section: Workers In Endoscopy Unitsmentioning

confidence: 99%

Effects of Glutaraldehyde Exposure on Human Health

Takigawa

Endo

2006

Journal of Occupational Health

248

147

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“…In fact, it has been suggested that many GA-induced symptoms are more related to procedural factors rather than airborne exposures (36). This is particularly important with respect to skin problems, many of which may arise from placing instruments into GA solution with ungloved hands.…”

Section: Reducing Occupational Exposurementioning

confidence: 99%

“…Accidental splashes of GA solution towards the face are the most likely situation leading to eye damage. Similarly, GA-induced skin irritation more likely occurs due to repeated accidental contact with GA solutions, rather than through vapor exposure (36). Aqueous GA solution is wellknown for its contact irritancy, with an irritation threshold believed to be around 1%, and with skin corrosion occurring at concentrations of approximately 45%.…”

Section: Occupational Disorders From Glutaraldehydementioning

confidence: 99%

“…• Irritant contact dermatitis (41) • Operating theater nurses (22,23,30,36) • Chronic dermatitis (39) • Laboratory technicians (33, 38) • Systemic sensitization (45,50) • X-ray technicians (31,32,43,46) • Occupational asthma (45)(46)(47)(48)50) • Cleaners, veterinarians (39,40,43) rigidly followed in workplaces that use GA (33,52). The enclosure of GA in using containers which are long and deep, and that have close-fitting lids is important.…”

Section: Reducing Occupational Exposurementioning

confidence: 99%

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Glutaraldehyde exposure and its occupational impact in the health care environment

Smith

Wang

2006

Environ Health Prev Med

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Despite the search for effective and less toxic substitutes, glutaraldehyde (GA) remains one of the few substances capable of high-level instrument disinfection in modern health care. Workers commonly affected include operating room nurses, radiographers, x-ray technicians and cleaners. Widespread hospital usage combined with its well-known irritant properties, has ensured an increase in occupationally-related illnesses during recent years. Operating room nurses, laboratory workers and x-ray technicians frequently contact GA in both the liquid and vapor form. Workplace exposure is usually dependent on job tasks, ventilation levels and the use of protective equipment. GA is a relatively potent irritant and sensitizer, with a well-documented history of symptoms following occupational exposure. Although mechanisms for GA toxicity have been postulated, research on the toxicological, teratogenic and carcinogenic potential of this chemical has shown inconsistent results. Reducing workplace exposure to its lowest possible level represents the most important hazard reduction strategy. This may be achieved by keeping GA containers tightly sealed when not in use, maintaining adequate ventilation levels and the rigid adherence to appropriate personal protective equipment. Substitution with automated cold sterilization machines may be another appropriate measure, while banning unnecessary practices such as GA fogging and its use as a surface disinfectant may also be helpful in reducing occupational exposure in the health care environment.

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Glutardialdehyd [MAK Value Documentation in German language, 2002]

2012

The MAK‐Collection for Occupational Health and Safety

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Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 35. Lieferung, Ausgabe 2002 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Erfahrungen beim Menschen Einmalige Exposition Allergene Wirkung Tierexperimentelle Befunde und In‐vitro‐Untersuchungen Subakute, subchronische und chronische Toxizität Bewertung

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Glutaraldehyde Exposures and Symptoms among Endoscopy Nurses in South Australia

Cited by 32 publications

References 13 publications

Effects of Glutaraldehyde Exposure on Human Health

Effects of Glutaraldehyde Exposure on Human Health

Glutaraldehyde exposure and its occupational impact in the health care environment

Glutardialdehyd [MAK Value Documentation in German language, 2002]

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