Glycemic Control and its Predictors among Diabetic Patients Attending a Tertiary Hospital in Nigeria: A Retrospective Observational Study

Yau, Adamu; Garba, Khalid M.; Yau, Shamsudeen; Ya’u, Jamilu

doi:10.30577/jba.v3i1.42

Cited by 5 publications

(5 citation statements)

References 33 publications

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“…32 In Nigeria, referral health facilities usually have the best expertise and this may explain why glycaemic control among patients with diabetes attending tertiary care facilities tends to be relatively good although a few studies have reported a contrary finding. 33 The findings of this study showed a statistically significant positive correlation between 10-year cardiovascular risk, using QRISK 3, and atherogenic index of plasma (r=0.368; p=0.002). Bo et al, also reported a significant association between AIP and the presence of cardiovascular risk factors.…”

Section: Resultsmentioning

confidence: 48%

Association between lipid indices and 10-year cardiovascular risk of a cohort of black Africans living with type 2 diabetes mellitus

Azeez

2021

J Adv Intern Med

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Introduction Diabetes mellitus is an established cardiovascular risk factor. Diabetes mellitus impairs lipid metabolism and enhances atherosclerosis development. Absolute lipid parameter are inadequate in predicting cardiovascular risk and some lipid indices have been reported to circumvent this deficiency. The objective of the study was to determine the association between these lipid indices and 10-year cardiovascular risk among black Africans with diabetes. Methods Seventy individuals (35 males and 35 females) living with diabetes who attended the diabetes clinic of a referral hospital in South-western Nigeria were recruited to the study. Ethical approval and participants’ informed consent were duly obtained. Fasting plasma glucose, fasting lipid profile and glycated haemoglobin were done using appropriate laboratory techniques. Atherogenic index of plasma, atherogenic coefficient, Castelli’s risk index I, Castelli’s risk index II and CHOLindex were calculated using appropriate formulae. QRISK 3 score was obtained using a validated calculator. The association between QRISK 3 and the lipid indices was determined using Pearson’s correlation. Results The mean age of the participants was 53.34 ± 9.57 years. The mean duration of diabetes mellitus among the participants was 6.29 ± 2.78 years. The mean HbA1c and FPG were 6.98±0.72% and 6.32±0.87 mmol/L respectively. The mean QRISK 3 score was 7.58±4.80. There was a statistically significant and positive correlation between QRISK 3 score and AIP, AC, CR I and CR II. CHOLindex did not significantly correlate with QRISK 3 score. Conclusion Among black Africans with diabetes, lipid indices (AIP, AC, CR I and CR II) significantly correlated with QRISK 3 score and therefore may be used as cheap markers of 10-year cardiovascular risk in these individuals.

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Section: Resultsmentioning

confidence: 48%

Association between lipid indices and 10-year cardiovascular risk of a cohort of black Africans living with type 2 diabetes mellitus

Azeez

2021

J Adv Intern Med

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“…A t o t a l o f n i n e 25,32,34,35,56,76,78,79,81 studies focused on glycaemic control and other treatment outcomes among diabetic patients. The 35,56,76 study participants were 1,861 and three studies showed that the provision of drug therapy counseling, education and follow-up text messages (electronic intervention) significantly reduced glycated haemoglobin (A1C) concentrations and fasting blood glucose (p<0.05) levels in patients with uncontrolled DM.…”

Section: 2 7 Tr E a T M E N T O U T C O M E Smentioning

confidence: 99%

Pharmacists-led diabetes care in Nigeria (2000-2022): A systematic review

2023

PSNNJP

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Background: Diabetes mellitus (DM) is a noncommunicable disease of global health concern, which is targeted for reduction according to the Sustainable Development Goals 3.4. The burden in Nigeria rose from 2.2% in 1997 to 5.77% in 2018. It is associated with high morbidity and mortality, thus requiring a collaborative care approach involving the patients and all healthcare providers to ensure optimal care. Pharmacists worldwide are involved in diabetes care, with evidence of positive outcomes, but the contributions of pharmacists in diabetes care have not been extensively reviewed in Nigeria. This review was aimed at describing the trends, geographical spread and quality of pharmacist-led diabetes care/research in Nigeria Methods: To identify diabetes-care research conducted by pharmacists in Nigeria, literature search for articles published between January 1, 2000 and June 5, 2022 was conducted, using databases such as PubMed/Medline, African Journal Online, Clinical Trials Registries, and Google Scholar. Medical subject headings (MeSH) and search terms combined with Boolean operators were among the keywords and search terms used for article identification. Only studies published in English language were considered. Results: Of the 62 studies retained for review, 51 were conducted in the southern zone of Nigeria (South-West 25, South-East 15 and South-South 11) and 11 in the north (North-East 6, North-Central 4 and North-West 1). Most of the studies (92%) were published between 2010 and 2022, with 83.9% conducted using cross-sectional design, 4.8% were Quasi-Randomized Studies and 11.3% were Randomized Controlled Trials. This review revealed that compared to usual care, patients who received pharmacist-delivered care had significantly improved medication adherence, quality of life and other clinical variables, with more cost-effective management outcomes. Conclusion:The contributions of pharmacists to diabetes care in Nigeria have significantly improved over the last decade. Majority of studies (82.3%) were conducted in the country's southern zone and only 11.3% were Randomized Controlled Trials with significant improvement in patients' treatment outcomes. More pharmacist-led high quality patient care research are recommended at the state (especially northern states) and national levels to improve on the current evidence of pharmacists' contribution to diabetes management in the Nigeria

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“…Almost one in 300 children develop T1DM [2]. These findings have been documented in many countries including both developed and developing countries [2,3]. It has been reported that, the incedence of T1DM is increasing by 3-4% per year globally in light of geographical variation with a high correlation between this incedence and socio-economic factors [4,5].…”

Section: Introductionmentioning

confidence: 99%

Treatment Outcome and Associated Factors among Type 1 Diabetic Children Admitted with DKA in Bahir Dar City Public Referral Hospital, Northwest, Ethiopia: A Cross-Sectional Study

Fentahun,

Silenat,

Tilaye

et al. 2023

Int Arch Endocrinol Clin Res

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Background: Length of hospital stay, complication and mortality are the primary outcomes that should be measured during diabetic ketoacidosis management. However, data associated with the length of stay, complications, and mortality rate due to diabetic ketoacidosis remains limited in Ethiopia. In addition, nonfiction is very scarce about factors associated with treatment outcomes starting from its initial presentation and the overall management process. Therefore, this study was aimed to assess the treatment outcomes of children admitted with diabetic ketoacidosis at the Felege Hiwot comprehensive referral hospital, North West, Ethiopia. Methods:A cross-sectional study was conducted among children admitted with diabetic keto acidosis between 2016 and 2021. Data were collected using the data abstruction tool. Then, stored in Epi-dataversion 4.6 and exported into STATA 14.0 statistical software for analysis. Catagorical variables were described using proportions and compared using the Chi-squre test; Whereas, continuous parametric variables with median and standard deviations were compared using parametric(t-test). Model goodness of fit and assumptions were checked. The association between independent variables and length of hospital stay was assessed using binary logistic regression. Finally, variables with p-value < 0.05 were considered as statistically significant. Result:The median length of hospital stay was 8 ± 6.2 days. 59.3% of the patients had along hospital stay (> 7 days). The majority of patients (97.5%) improved and were discharged with 14.2% complications and 4(2.5%) died in the hospital. Factors that affected longer hospital stay were Residence (aOR = 4.31; 95CI = 1.25-14.80), family history of diabetes (aOR = 0.12; 95% CI = 0.02-0.64), glycemia at addmision (aOR =1.01; 95% CI = 1.00-1.02), insulin skipping (aOR = 0.08; 95% CI = 0.01-0.98), abdominal pain (aOR = 4.28; 95% CI = 1.11-15.52) and time in which the patient get out of diabetic ketoacidosis (aOR = 6.39; 95% CI = 1.09-37.50). Conclusion:Majority of patients showed improvement and were discharged to their homes after a long hospital stay and with a very low mortality rate followed by complications (14.2%). The time in which the majority of patients got out of diabetic ketoacidosis were between 24-48 hours. Thus, to achieve intended treatment outcome early in time, clinicians and other stakeholders should focus on diabetic ketoacidosis presentation and precipitating factors with possible multicenter studies.

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Glycemic Control and its Predictors among Diabetic Patients Attending a Tertiary Hospital in Nigeria: A Retrospective Observational Study

Cited by 5 publications

References 33 publications

Association between lipid indices and 10-year cardiovascular risk of a cohort of black Africans living with type 2 diabetes mellitus

Association between lipid indices and 10-year cardiovascular risk of a cohort of black Africans living with type 2 diabetes mellitus

Pharmacists-led diabetes care in Nigeria (2000-2022): A systematic review

Treatment Outcome and Associated Factors among Type 1 Diabetic Children Admitted with DKA in Bahir Dar City Public Referral Hospital, Northwest, Ethiopia: A Cross-Sectional Study

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