2006
DOI: 10.1248/bpb.29.1391
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Glycoprotein (90 kDa) Isolated from Opuntia ficus-indica var. saboten MAKINO Lowers Plasma Lipid Level through Scavenging of Intracellular Radicals in Triton WR-1339-Induced Mice

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Cited by 39 publications
(17 citation statements)
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“…Recent studies in vivo and/or in vitro showed that extracts from the fruit and stems of different Opuntia species have various biological activities, including anticancer, antiviral, anti-inflammatory, antidiabetic and antioxidant properties [10][11][12][13][14]. In the present study, we provide evidence suggesting that polysaccharides from Opuntia Milpa Alta have potent neuroprotective properties against cerebral ischemia.…”
Section: Discussionsupporting
confidence: 59%
See 1 more Smart Citation
“…Recent studies in vivo and/or in vitro showed that extracts from the fruit and stems of different Opuntia species have various biological activities, including anticancer, antiviral, anti-inflammatory, antidiabetic and antioxidant properties [10][11][12][13][14]. In the present study, we provide evidence suggesting that polysaccharides from Opuntia Milpa Alta have potent neuroprotective properties against cerebral ischemia.…”
Section: Discussionsupporting
confidence: 59%
“…Concurrently, studies have shown that Opuntia possess neuroprotective effects via its antioxidant actions [9]. With deep research, researchers have extracted all kinds of the low-molecular weight effective compounds from Opuntia species, for example, carotenoids, flavonols, dihydroflavonols, flavanonols, beta-sterols and betalains [10][11][12][13][14]. Bioactive polysaccharides have also been isolated and characterized [15][16][17].…”
Section: Introductionmentioning
confidence: 99%
“…Lim et al have purified a 36 kDa glycoprotein having hypolipidemic and antioxidative property from the plant Rhus verniciflua [77]. Lim et al also isolated a 90 kDa glycoprotein from Opuntia ficus-indica which has been found to lower plasma lipid level by scavenging free radicals [78]. Sivapriya and Srinivas have isolated and purified a novel antioxidant protein from the water extract of Solanum torvum seeds [79].…”
Section: Discussionmentioning
confidence: 99%
“…As a natural component, glycoproteins have shown biopharmacological activities such as anti-tumor and hypolipidemic effects with their hygroscopic characteristics and high polarity (Oh and Lim, 2006;Ooi and Liu, 2000). Our previous studies have handled the potential of anti-allergic property of CTB glycoprotein on environmental hormones-caused allergy-like responses in mast cells (Oh and Lim, 2010;Park and Lim, 2010).…”
Section: Discussionmentioning
confidence: 99%