Gnathostomiasis: Import from Laos

Hennies, Felix; Jappe, Uta; Kapaun, Annette; Enk, Alexander

doi:10.1111/j.1610-0387.2006.05942.x

Cited by 12 publications

(6 citation statements)

References 6 publications

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“…Gnathostomiasis is most commonly encountered in European and North American healthcare settings in returning travellers from South-East Asia62 and South and Central America,63 64 though imports from Africa65 and an endemic case in Australia66 have been reported. The major risk factor for gnathostomiasis is consumption of raw freshwater seafood in endemic regions 67.…”

Section: Discussionmentioning

confidence: 99%

Imported gnathostomiasis manifesting as cutaneous larva migrans and Löffler’s syndrome

Hamilton

Agranoff²

2018

BMJ Case Reports

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Here, we report an unusual case of invasive gnathostomiasis in a returning traveller, with a shifting pattern of relapsing cutaneous disease. The previously fit and well 32-year-old man first presented with serpiginous, pruriginous erythematous tracks characteristic of cutaneous larva migrans shortly after returning from South-East Asia. He was systemically well with no other symptoms. After ivermectin therapy, he re-presented with respiratory symptoms, peripheral eosinophilia and transient pulmonary infiltrates; the classic triad of Löffler's syndrome associated with invasive helminth infection. immunoblot was positive. After a second round of ivermectin therapy his respiratory symptoms resolved, but the patient's cutaneous disease relapsed repeatedly over months, with migratory erythematous swellings appearing and settling after a few days. He was treated with a 21-day course of albendazole and is lesion free at 40 weeks post initial presentation.

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Section: Discussionmentioning

confidence: 99%

Imported gnathostomiasis manifesting as cutaneous larva migrans and Löffler’s syndrome

Hamilton

Agranoff²

2018

BMJ Case Reports

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“…4 A localização usual é a cutânea, mas a larva pode migrar para outros órgãos e sistemas, como olhos, pulmões e sistema nervoso central. [5][6][7] Na Tailândia a gnatostomíase é uma das principais causas de hemorragia subaracnóide, correspondendo a 6% dos casos em adultos.…”

Section: Discussionunclassified

“…2,4,5 A larva do Gnathostoma sp pode causar doença exclusivamente cutânea ou disseminada para outros órgãos e sistemas, como olhos, pulmões e sistema nervoso central. 4,6,7 Este artigo relata o caso de paciente que esteve em viagem ao Peru, onde ingeriu ceviche, apresentando duas semanas após quadro clí-nico compatível com gnatostomíase. No Brasil, até o momento, não existem registros da doença, tendo sido esse caso notificado à Anvisa em março de 2008.…”

Section: Introductionunclassified

Gnatostomíase no Brasil: relato de caso

Dani

Mota

Sanchotene

et al. 2009

An. Bras. Dermatol.

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Resumo: A gnatostomíase é parasitose endêmica em alguns países asiáticos, causada pela ingestão da larva do nematódio Gnathostoma sp, que pode ocorrer no consumo de carne crua de peixes de água doce. Atinge vários órgãos, entre eles a pele, manifestando-se frequentemente como lesão subcutânea migratória. Países da América Central e do Sul como México e Peru vêm apresentando número crescente de casos da doença desde 1970. Este trabalho registra o primeiro caso notificado e publicado no Brasil e alerta para o surgimento dessa doença em áreas anteriormente não endêmicas. Relata-se caso de paciente, com história de viagem ao Peru, que evoluiu com quadro cutâneo compatível com gnatostomíase. Palavras-chave: Gnathostoma; Helmintos; Paniculite Abstract: Gnathostomiasis is an endemic disease in Asian countries caused by the ingestion of larval stage of Gnathostoma sp roundworms that may be acquired by eating raw fresh-water fish. It can reach many organs and the skin is one of them, characterized by creeping eruptions and/or migrating erythema. Since 1970 the number of patients affected seems to be increasing in Central and South America countries like Mexico and Peru. This is the first notification and publication of gnathostomiasis in Brazil, and it serves as an alert to the possibility of the emergence of this disease in non-endemic areas. We report a case of a man who traveled to Peru and developed cutaneous features accordant with gnathostomiasis.

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“…Human gnathostomiasis is caused by infection with larval gnathostomes, which is characterized clinically by creeping eruption in subcutaneous and intermuscular tissues due to migrating larvae [1]. It is also known that Gnathostoma larvae occasionally invade the visceral organs, including the liver, lungs, eyes, and even the brain [1,2].Human gnathostomiasis is known to be prevalent in Southeast Asia, including Thailand, Lao PDR, and Myanmar, but this nematode infection is very rare in Cambodia [3][4][5][6][7][8][9][10][11]. Only 1 case of ocular gnathostomiasis was reported in Cambodia [12].…”

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confidence: 99%

Detection of Gnathostoma spinigerum Advanced 3rd-Stage Larvae in the Chinese Edible Frog, Hoplobatrachus rugulosus, from Local Markets in Phnom Penh, Cambodia

et al. 2021

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The Chinese edible frogs, Hoplobatrachus rugulosus (n=20), and the striped snakehead fish, Channa striata (n=34), were purchased from local markets in 3 administrative regions of Cambodia (Phnom Penh, Pursat, and Takeo Provinces) from May 2017 to April 2019, and their infection status with Gnathostoma sp. larvae was investigated. The frogs and fish were transported to the laboratory with ice and examined using the artificial digestion method. Advanced 3rd-stage larvae (AdL3) of Gnathostoma spinigerum, 24 in total number (1-6 larvae/frog), were detected from 6 (60.0%) out of 10 frogs purchased from Phnom Penh. No gnathostome larvae were detected in 10 frogs purchased from Takeo Province and 34 snakeheads from Phnom Penh, Pursat, and Takeo Provinces. AdL3 isolated from the frogs were 2.55- 3.90 mm long and 0.31-0.36 mm wide. They had a characteristic head bulb (0.081×0.191 mm in average size) with 4 rows of hooklets, a muscular long esophagus (0.950-1.230 mm long), and 2 pairs of cervical sacs (0.530-0.890 mm long). The average number of hooklets in the 1st, 2nd, 3rd, and 4th rows was 41, 45, 48, and 51, respectively. These features were consistent with G. spinigerum AdL3. By the present study, it has been first confirmed that the Chinese edible frog, H. rugulosus, from Phnom Penh serves as a second intermediate host for G. spinigerum, although their intensity of infection was not so high compared to other previously reported localities.

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Gnathostomiasis: Import from Laos

Cited by 12 publications

References 6 publications

Imported gnathostomiasis manifesting as cutaneous larva migrans and Löffler’s syndrome

Imported gnathostomiasis manifesting as cutaneous larva migrans and Löffler’s syndrome

Gnatostomíase no Brasil: relato de caso

Detection of Gnathostoma spinigerum Advanced 3rd-Stage Larvae in the Chinese Edible Frog, Hoplobatrachus rugulosus, from Local Markets in Phnom Penh, Cambodia

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