Going global – Travel and the 2019 novel coronavirus

Rodríguez‐Morales, Alfonso J.; MacGregor, Kirsten; Kanagarajah, Sanch; Patel, Dipti; Schlagenhauf, Patricia

doi:10.1016/j.tmaid.2020.101578

Cited by 295 publications

(273 citation statements)

References 31 publications

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“…Virus particles spread through the respiratory mucosa, initially using the ACE2 receptor at ciliated bronchial epithelial cells, and then infect other cells. This induces a cytokine storm in the body and generate a series of immune responses, that cause changes in peripheral white blood cells and immune cells such as lymphocytes [56,57].…”

Section: Discussionmentioning

confidence: 99%

“…The results of this systematic review highlight the clinical, laboratory, and imaging findings that may assist clinicians anywhere in the globe in suspecting the possibility of COVID-19 infection in those with recent travel to areas with ongoing transmission or among contacts of confirmed cases. Early recognition of cases will allow clinicians to ensure adequate clinical monitoring, institution of supportive interventions, and preventing further transmission by implementing of infection control measures [29,56,63]. There is a need for prospective studies to evaluate the epidemiology, pathogenesis, duration of viral shedding, and the clinical spectrum of disease associated with this emerging viral infection [29,56,63].…”

Section: Discussionmentioning

confidence: 99%

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Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

Rodríguez‐Morales

Cardona-Ospina

Gutiérrez‐Ocampo

et al. 2020

Travel Medicine and Infectious Disease

2,101

124

1,591

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Methods:We performed a systematic literature review with meta-analysis, using three databases to assess clinical, laboratory, imaging features, and outcomes of COVID-19 confirmed cases. Observational studies and also case reports, were included, and analyzed separately. We performed a random-effects model meta-analysis to calculate the pooled prevalence and 95% confidence interval (95%CI).Results: 660 articles were retrieved for the time frame (1/1/2020-2/23/2020). After screening, 27 articles were selected for full-text assessment, 19 being finally included for qualitative and quantitative analyses. Additionally, 39 case report articles were included and analyzed separately. For 656 patients, fever (88.7%, 95%CI 84.5-92.9%), cough (57.6%, 40.8-74.4%) and dyspnea (45.6%, 10.9-80.4%) were the most prevalent manifestations. Among the patients, 20.3% (95%CI 10.0-30.6%) required intensive care unit (ICU), 32.8% presented with acute respiratory distress syndrome (ARDS) (95%CI 13.7-51.8), 6.2% (95%CI 3.1-9.3) with shock. Some 13.9% (95%CI 6.2-21.5%) of hospitalized patients had fatal outcomes (case fatality rate, CFR).Conclusion: COVID-19 brings a huge burden to healthcare facilities, especially in patients with comorbidities. ICU was required for approximately 20% of polymorbid, COVID-19 infected patients and hospitalization was associated with a CFR of over 13%. As this virus spreads globally, countries need to urgently prepare human resources, infrastructure and facilities to treat severe COVID-19.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis

Rodríguez‐Morales

Cardona-Ospina

Gutiérrez‐Ocampo

et al. 2020

Travel Medicine and Infectious Disease

2,101

124

1,591

View full text Add to dashboard Cite

show abstract

“…Mapping the incidence of the COVID-19 hotspot in Iran -Implications for After the first two months of the epidemics of Coronavirus Disease 2019 (COVID-19) in the world [1,2], caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), multiple epidemiological assessments in countries from Asia, Europe, and North America have been published [3,4]. Nevertheless, there are countries, with a rapid increase and a high number of cases, with a lack of studies.…”

Section: Letter To the Editormentioning

confidence: 99%

Mapping the incidence of the COVID-19 hotspot in Iran – Implications for Travellers

Arab-Mazar

Sah

Rabaan

et al. 2020

Travel Medicine and Infectious Disease

154

117

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“…Since January 7, 2020, the quarantine and detection measures of travelers from the city of Wuhan, have been improved at the points of Current recommendations [2,3], for people traveling to Japan, may undoubtedly change rapidly, in any direction, while the country has been aiming to contain the transmission as much as possible. In China, most of the professional sports leagues have been canceled their seasons, especially football and athletic disciplines, ski, hockey, among many others, but even qualifying competitions for the Olympic Games.…”

mentioning

confidence: 99%